desmosome Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. (Gene Ontology, GO_0030057)
External Link http://amigo.geneontology.org/amigo/term/GO:0030057
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Genes

22 proteins localized to the desmosome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CDSN corneodesmosin
DSC1 desmocollin 1
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG2 desmoglein 2
DSG3 desmoglein 3
DSG4 desmoglein 4
DSP desmoplakin
EVPL envoplakin
JAM3 junctional adhesion molecule 3
JUP junction plakoglobin
KAZN kazrin, periplakin interacting protein
PERP PERP, TP53 apoptosis effector
PKP1 plakophilin 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PKP4 plakophilin 4
PNN pinin, desmosome associated protein
PPL periplakin
UBA1 ubiquitin-like modifier activating enzyme 1