desmosome Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. (Gene Ontology, GO_0030057)
External Link http://amigo.geneontology.org/amigo/term/GO:0030057
Similar Terms
Downloads & Tools

Genes

23 proteins localized to the desmosome cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDSN corneodesmosin
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG2 desmoglein 2
DSG3 desmoglein 3
DSG4 desmoglein 4
DSPP dentin sialophosphoprotein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
JAM3 junctional adhesion molecule 3
JUP junction plakoglobin
KAZN kazrin, periplakin interacting protein
KLHL24 kelch-like family member 24
KRT80 keratin 80, type II
PERP PERP, TP53 apoptosis effector
PKP1 plakophilin 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PKP4 plakophilin 4
POF1B premature ovarian failure, 1B
RCAN1 regulator of calcineurin 1
UBA1 ubiquitin-like modifier activating enzyme 1