desmosome Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. (Gene Ontology, GO_0030057)
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Genes

21 genes co-occuring with the biological term desmosome in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
CAV1 caveolin 1, caveolae protein, 22kDa
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CKAP4 cytoskeleton-associated protein 4
CTNND1 catenin (cadherin-associated protein), delta 1
DSC2 desmocollin 2
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG2 desmoglein 2
DSG3 desmoglein 3
DSP desmoplakin
EGFR epidermal growth factor receptor
JUP junction plakoglobin
KIF2A kinesin heavy chain member 2A
KTN1 kinectin 1 (kinesin receptor)
PKP1 plakophilin 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PKP4 plakophilin 4
PRKCA protein kinase C, alpha
SFN stratifin