detached acrosome Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description detachment or loss of adhesion of the acrosome cap from the sperm head nucleus (Mammalian Phenotype Ontology, MP_0009231)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009231
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Genes

12 gene mutations causing the detached acrosome phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AURKC aurora kinase C
CSNK2A2 casein kinase 2, alpha prime polypeptide
DPY19L2 dpy-19-like 2 (C. elegans)
FHL5 four and a half LIM domains 5
FSHR follicle stimulating hormone receptor
GOPC golgi-associated PDZ and coiled-coil motif containing
H1FNT H1 histone family, member N, testis-specific
NCOA2 nuclear receptor coactivator 2
RIMBP3 RIMS binding protein 3
RXRB retinoid X receptor, beta
SEPT12 septin 12
TNP2 transition protein 2 (during histone to protamine replacement)