develop Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

427 genes co-occuring with the biological term develop in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM33 ADAM metallopeptidase domain 33
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHRR aryl-hydrocarbon receptor repressor
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPP alkaline phosphatase, placental
AMACR alpha-methylacyl-CoA racemase
ANGPT1 angiopoietin 1
ANKK1 ankyrin repeat and kinase domain containing 1
APC adenomatous polyposis coli
APCS amyloid P component, serum
APH1B APH1B gamma secretase subunit
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN1 ataxin 1
ATXN2 ataxin 2
AURKA aurora kinase A
AURKB aurora kinase B
BCAR1 breast cancer anti-estrogen resistance 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2L1 BCL2-like 1
BDKRB2 bradykinin receptor B2
BEST1 bestrophin 1
BMP4 bone morphogenetic protein 4
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C3 complement component 3
C3ORF35 chromosome 3 open reading frame 35
C9ORF72 chromosome 9 open reading frame 72
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACYBP calcyclin binding protein
CARD9 caspase recruitment domain family, member 9
CASQ2 calsequestrin 2 (cardiac muscle)
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCM2 cerebral cavernous malformation 2
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD209 CD209 molecule
CD24 CD24 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD70 CD70 molecule
CD80 CD80 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK11B cyclin-dependent kinase 11B
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEL carboxyl ester lipase
CFB complement factor B
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHIT1 chitinase 1 (chitotriosidase)
CHMP1A charged multivesicular body protein 1A
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COL7A1 collagen, type VII, alpha 1
COMT catechol-O-methyltransferase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSD cathepsin D
CTSL cathepsin L
CTSS cathepsin S
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DEL22Q11.2 Chromosome 22q11.2 deletion syndrome, distal
DRD2 dopamine receptor D2
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ENG endoglin
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
F13B coagulation factor XIII, B polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FAM168A family with sequence similarity 168, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXW8 F-box and WD repeat domain containing 8
FCAR Fc fragment of IgA receptor
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR4 fibroblast growth factor receptor 4
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FMO1 flavin containing monooxygenase 1
FMR1 fragile X mental retardation 1
FOXG1 forkhead box G1
FOXP3 forkhead box P3
FRG1 FSHD region gene 1
FSHR follicle stimulating hormone receptor
FTO fat mass and obesity associated
GAB3 GRB2-associated binding protein 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCG glucagon
GJA1 gap junction protein, alpha 1, 43kDa
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GP6 glycoprotein VI (platelet)
GPC3 glypican 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRN granulin
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
GZMM granzyme M (lymphocyte met-ase 1)
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HOXD13 homeobox D13
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTRA1 HtrA serine peptidase 1
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHD immunoglobulin heavy constant delta
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL12B interleukin 12B
IL16 interleukin 16
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
IL4 interleukin 4
IL6 interleukin 6
INHBA inhibin, beta A
INS insulin
IRAK4 interleukin-1 receptor-associated kinase 4
IRF4 interferon regulatory factor 4
IRS1 insulin receptor substrate 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK2 Janus kinase 2
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF20A kinesin family member 20A
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF1 Kruppel-like factor 1 (erythroid)
KRAS Kirsten rat sarcoma viral oncogene homolog
LCT lactase
LDLR low density lipoprotein receptor
LGI1 leucine-rich, glioma inactivated 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LMNA lamin A/C
LPL lipoprotein lipase
LRP2 low density lipoprotein receptor-related protein 2
LRRK2 leucine-rich repeat kinase 2
LTBP1 latent transforming growth factor beta binding protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGED4 melanoma antigen family D4
MAOA monoamine oxidase A
MAP2K4 mitogen-activated protein kinase kinase 4
MAPT microtubule-associated protein tau
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MC4R melanocortin 4 receptor
MCOLN1 mucolipin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MIR140 microRNA 140
MIR200C microRNA 200c
MIR211 microRNA 211
MIR27A microRNA 27a
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSRA methionine sulfoxide reductase A
MTCP1 mature T-cell proliferation 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTM1 myotubularin 1
MTSS1 metastasis suppressor 1
MTTP microsomal triglyceride transfer protein
MUC1 mucin 1, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYBBP1A MYB binding protein (P160) 1a
MYBPC2 myosin binding protein C, fast type
MYD88 myeloid differentiation primary response 88
MYH9 myosin, heavy chain 9, non-muscle
MYPN myopalladin
NAMPT nicotinamide phosphoribosyltransferase
NELL1 NEL-like 1 (chicken)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPA natriuretic peptide A
NPR2 natriuretic peptide receptor 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTS neurotensin
NUP98 nucleoporin 98kDa
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PALB2 partner and localizer of BRCA2
PANX1 pannexin 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PAX4 paired box 4
PAX8 paired box 8
PCDH10 protocadherin 10
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PDS5B PDS5 cohesin associated factor B
PDYN prodynorphin
PEBP1 phosphatidylethanolamine binding protein 1
PEMT phosphatidylethanolamine N-methyltransferase
PGC progastricsin (pepsinogen C)
PGF placental growth factor
PGR progesterone receptor
PGRMC1 progesterone receptor membrane component 1
PHOX2B paired-like homeobox 2b
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PINK1 PTEN induced putative kinase 1
PKP2 plakophilin 2
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
PLIN2 perilipin 2
PLK1 polo-like kinase 1
PLP1 proteolipid protein 1
PNPLA3 patatin-like phospholipase domain containing 3
POLH polymerase (DNA directed), eta
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRNP prion protein
PRSS1 protease, serine, 1 (trypsin 1)
PSEN1 presenilin 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRJ protein tyrosine phosphatase, receptor type, J
PTX3 pentraxin 3, long
PYY peptide YY
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RECQL4 RecQ protein-like 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RET ret proto-oncogene
RETN resistin
RNASEH2B ribonuclease H2, subunit B
RNLS renalase, FAD-dependent amine oxidase
RUNX1 runt-related transcription factor 1
S100A1 S100 calcium binding protein A1
S100B S100 calcium binding protein B
SALL4 spalt-like transcription factor 4
SCN5A sodium channel, voltage gated, type V alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SPINK1 serine peptidase inhibitor, Kazal type 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STK17A serine/threonine kinase 17a
TARDBP TAR DNA binding protein
TBX21 T-box 21
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMEM132D transmembrane protein 132D
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOP2A topoisomerase (DNA) II alpha 170kDa
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TP73 tumor protein p73
TPH2 tryptophan hydroxylase 2
TPM3 tropomyosin 3
TPMT thiopurine S-methyltransferase
TPO thyroid peroxidase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TSG101 tumor susceptibility 101
TSPY1 testis specific protein, Y-linked 1
TTR transthyretin
TUSC2 tumor suppressor candidate 2
TYR tyrosinase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UNC93B1 unc-93 homolog B1 (C. elegans)
USF1 upstream transcription factor 1
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VTN vitronectin
WFDC2 WAP four-disulfide core domain 2
WNK4 WNK lysine deficient protein kinase 4
WNT7A wingless-type MMTV integration site family, member 7A
WWOX WW domain containing oxidoreductase
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZEB1 zinc finger E-box binding homeobox 1