dexamethasone-2079 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dexamethasone-2079 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPTL4 angiopoietin-like 4
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOM apolipoprotein M
ARTN artemin
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF66 chromosome 19 open reading frame 66
CACYBP calcyclin binding protein
CASZ1 castor zinc finger 1
CCL20 chemokine (C-C motif) ligand 20
CD40 CD40 molecule, TNF receptor superfamily member 5
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CRY2 cryptochrome circadian clock 2
CXCL5 chemokine (C-X-C motif) ligand 5
DCAF4 DDB1 and CUL4 associated factor 4
DSCR3 Down syndrome critical region 3
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EFNA3 ephrin-A3
EFNB2 ephrin-B2
ELF1 E74-like factor 1 (ets domain transcription factor)
EMP1 epithelial membrane protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FBLN1 fibulin 1
FZD1 frizzled class receptor 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLUL glutamate-ammonia ligase
HEG1 heart development protein with EGF-like domains 1
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HPS4 Hermansky-Pudlak syndrome 4
IL6R interleukin 6 receptor
IRS2 insulin receptor substrate 2
ITGA10 integrin, alpha 10
JADE2 jade family PHD finger 2
KLF6 Kruppel-like factor 6
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LHX6 LIM homeobox 6
LMAN1 lectin, mannose-binding, 1
MAX MYC associated factor X
MBTPS2 membrane-bound transcription factor peptidase, site 2
MIIP migration and invasion inhibitory protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNS1 meiosis-specific nuclear structural 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSH6 mutS homolog 6
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MTMR1 myotubularin related protein 1
NADK NAD kinase
NAV2 neuron navigator 2
NEBL nebulette
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NID2 nidogen 2 (osteonidogen)
NNMT nicotinamide N-methyltransferase
NOD1 nucleotide-binding oligomerization domain containing 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
OXLD1 oxidoreductase-like domain containing 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PER1 period circadian clock 1
PLAT plasminogen activator, tissue
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTGES prostaglandin E synthase
PTPRR protein tyrosine phosphatase, receptor type, R
RBM19 RNA binding motif protein 19
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SNAI2 snail family zinc finger 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SUGP1 SURP and G patch domain containing 1
TH tyrosine hydroxylase
TLR2 toll-like receptor 2
TMEM231 transmembrane protein 231
TNIK TRAF2 and NCK interacting kinase
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UGT8 UDP glycosyltransferase 8
VWA1 von Willebrand factor A domain containing 1
YOD1 YOD1 deubiquitinase
YY2 YY2 transcription factor
ZNF273 zinc finger protein 273
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKRD10 ankyrin repeat domain 10
ARL14 ADP-ribosylation factor-like 14
ARRB2 arrestin, beta 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
BANK1 B-cell scaffold protein with ankyrin repeats 1
BDNF brain-derived neurotrophic factor
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C7ORF69 chromosome 7 open reading frame 69
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCDC91 coiled-coil domain containing 91
CCRL2 chemokine (C-C motif) receptor-like 2
CD70 CD70 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CLDN14 claudin 14
CNGB3 cyclic nucleotide gated channel beta 3
COL5A2 collagen, type V, alpha 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTAGE9 CTAGE family, member 9
CTH cystathionine gamma-lyase
CTNNBIP1 catenin, beta interacting protein 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAL4 dynein, axonemal, light chain 4
DUSP8 dual specificity phosphatase 8
EGF epidermal growth factor
ERF Ets2 repressor factor
ETV4 ets variant 4
FAM110B family with sequence similarity 110, member B
FBRS fibrosin
FBXO2 F-box protein 2
FJX1 four jointed box 1 (Drosophila)
GBX2 gastrulation brain homeobox 2
GCA grancalcin, EF-hand calcium binding protein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H1F0 H1 histone family, member 0
HDAC4 histone deacetylase 4
HMOX1 heme oxygenase 1
HYI hydroxypyruvate isomerase (putative)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1B interleukin 1, beta
IL24 interleukin 24
IL33 interleukin 33
IMPACT impact RWD domain protein
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM5C lysine (K)-specific demethylase 5C
KIAA0895 KIAA0895
KIAA1549L KIAA1549-like
LIF leukemia inhibitory factor
LMNB1 lamin B1
LYPD1 LY6/PLAUR domain containing 1
MAGEF1 melanoma antigen family F1
MMP13 matrix metallopeptidase 13
MNX1 motor neuron and pancreas homeobox 1
NLK nemo-like kinase
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
OASL 2'-5'-oligoadenylate synthetase-like
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAU plasminogen activator, urokinase
POLE polymerase (DNA directed), epsilon, catalytic subunit
POMT2 protein-O-mannosyltransferase 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTGFR prostaglandin F receptor (FP)
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB3A RAB3A, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF170 ring finger protein 170
RUNX1-IT1 RUNX1 intronic transcript 1
SIDT1 SID1 transmembrane family, member 1
SKI SKI proto-oncogene
SLC25A40 solute carrier family 25, member 40
SLC35F6 solute carrier family 35, member F6
TBC1D17 TBC1 domain family, member 17
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THAP1 THAP domain containing, apoptosis associated protein 1
TMC5 transmembrane channel-like 5
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSKU tsukushi, small leucine rich proteoglycan
UBTD1 ubiquitin domain containing 1
UBTF upstream binding transcription factor, RNA polymerase I
UNKL unkempt family zinc finger-like
VEGFB vascular endothelial growth factor B
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF32 zinc finger protein 32
ZNF408 zinc finger protein 408
ZNF426 zinc finger protein 426