dexamethasone-255 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the dexamethasone-255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AGFG2 ArfGAP with FG repeats 2
AGTR2 angiotensin II receptor, type 2
AGXT alanine-glyoxylate aminotransferase
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
APOL3 apolipoprotein L, 3
AQP3 aquaporin 3 (Gill blood group)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AXIN1 axin 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBC3 BCL2 binding component 3
C20ORF27 chromosome 20 open reading frame 27
CA6 carbonic anhydrase VI
CADM3 cell adhesion molecule 3
CCL13 chemokine (C-C motif) ligand 13
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD19 CD19 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CDRT1 CMT1A duplicated region transcript 1
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP41 centrosomal protein 41kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CRYAB crystallin, alpha B
DNAH3 dynein, axonemal, heavy chain 3
DOK2 docking protein 2, 56kDa
DUS2 dihydrouridine synthase 2
EDA ectodysplasin A
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FAR2 fatty acyl CoA reductase 2
FBLN5 fibulin 5
FGF16 fibroblast growth factor 16
FSTL4 follistatin-like 4
GOSR2 golgi SNAP receptor complex member 2
GREB1L growth regulation by estrogen in breast cancer-like
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM1 glutamate receptor, metabotropic 1
GSTCD glutathione S-transferase, C-terminal domain containing
HSPB11 heat shock protein family B (small), member 11
IGFBP3 insulin-like growth factor binding protein 3
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
ITGB1BP1 integrin beta 1 binding protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLHL1 kelch-like family member 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARC1 mitochondrial amidoxime reducing component 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MST1 macrophage stimulating 1
MTERF4 mitochondrial transcription termination factor 4
NCF4 neutrophil cytosolic factor 4, 40kDa
NCKIPSD NCK interacting protein with SH3 domain
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP160 nucleoporin 160kDa
OVOL1 ovo-like zinc finger 1
PCDHGA3 protocadherin gamma subfamily A, 3
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PLXNB3 plexin B3
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
RAB3A RAB3A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RNF141 ring finger protein 141
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RRAS related RAS viral (r-ras) oncogene homolog
SAMHD1 SAM domain and HD domain 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SIDT2 SID1 transmembrane family, member 2
SIK3 SIK family kinase 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SPN sialophorin
STAB2 stabilin 2
STAG3 stromal antigen 3
STS steroid sulfatase (microsomal), isozyme S
TAOK2 TAO kinase 2
TBX5 T-box 5
TES testin LIM domain protein
TGM2 transglutaminase 2
TGM5 transglutaminase 5
TLN2 talin 2
TMEM143 transmembrane protein 143
TMEM151B transmembrane protein 151B
TMPRSS5 transmembrane protease, serine 5
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNIK TRAF2 and NCK interacting kinase
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSHZ2 teashirt zinc finger homeobox 2
WNT2B wingless-type MMTV integration site family, member 2B
ZNF287 zinc finger protein 287
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
AHR aryl hydrocarbon receptor
ARPIN actin-related protein 2/3 complex inhibitor
ASTE1 asteroid homolog 1 (Drosophila)
BACE1 beta-site APP-cleaving enzyme 1
BARX2 BARX homeobox 2
BCORL1 BCL6 corepressor-like 1
C1ORF159 chromosome 1 open reading frame 159
C1ORF95 chromosome 1 open reading frame 95
C1QTNF1 C1q and tumor necrosis factor related protein 1
C2CD2 C2 calcium-dependent domain containing 2
CAV3 caveolin 3
CCNK cyclin K
CCS copper chaperone for superoxide dismutase
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLSTN2 calsyntenin 2
CNPY3 canopy FGF signaling regulator 3
COPZ2 coatomer protein complex, subunit zeta 2
CORO2A coronin, actin binding protein, 2A
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
ELP6 elongator acetyltransferase complex subunit 6
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
FKBP10 FK506 binding protein 10, 65 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMD1 FERM domain containing 1
FXYD1 FXYD domain containing ion transport regulator 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GLMN glomulin, FKBP associated protein
GLS2 glutaminase 2 (liver, mitochondrial)
GPR21 G protein-coupled receptor 21
HBD hemoglobin, delta
HINFP histone H4 transcription factor
HOXB1 homeobox B1
HOXB2 homeobox B2
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL12RB1 interleukin 12 receptor, beta 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIFAP3 kinesin-associated protein 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF15 Kruppel-like factor 15
KLF2 Kruppel-like factor 2
KRT1 keratin 1, type II
KRT75 keratin 75, type II
LENEP lens epithelial protein
LIN28A lin-28 homolog A (C. elegans)
LMTK1 lemur tail kinase 1
LOC440895 two pore channel 3 pseudogene
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
MC5R melanocortin 5 receptor
MCOLN1 mucolipin 1
MEGF6 multiple EGF-like-domains 6
MFSD12 major facilitator superfamily domain containing 12
MICB MHC class I polypeptide-related sequence B
MRPL41 mitochondrial ribosomal protein L41
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NLRX1 NLR family member X1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXF2 nuclear RNA export factor 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHB6 protocadherin beta 6
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PHC1 polyhomeotic homolog 1 (Drosophila)
PHOX2A paired-like homeobox 2a
PRMT7 protein arginine methyltransferase 7
PYGM phosphorylase, glycogen, muscle
RAB4B RAB4B, member RAS oncogene family
RDH8 retinol dehydrogenase 8 (all-trans)
RGS17 regulator of G-protein signaling 17
RHOH ras homolog family member H
RNFT2 ring finger protein, transmembrane 2
S100A4 S100 calcium binding protein A4
SAG S-antigen; retina and pineal gland (arrestin)
SNX17 sorting nexin 17
SOCS7 suppressor of cytokine signaling 7
TAOK1 TAO kinase 1
TCAP titin-cap
TG thyroglobulin
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TOLLIP toll interacting protein
TRAPPC12 trafficking protein particle complex 12
TTLL3 tubulin tyrosine ligase-like family member 3
TUBA8 tubulin, alpha 8
TUBAL3 tubulin, alpha-like 3
UNC93B1 unc-93 homolog B1 (C. elegans)
ZNF184 zinc finger protein 184
ZNF408 zinc finger protein 408
ZNF446 zinc finger protein 446
ZXDC ZXD family zinc finger C