dexamethasone-5797 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dexamethasone-5797 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACAN aggrecan
ACSM3 acyl-CoA synthetase medium-chain family member 3
AGRN agrin
ANGPTL4 angiopoietin-like 4
ANK2 ankyrin 2, neuronal
ANXA10 annexin A10
ARNT aryl hydrocarbon receptor nuclear translocator
ATP10A ATPase, class V, type 10A
ATP9A ATPase, class II, type 9A
ATXN7L1 ataxin 7-like 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTN3A2 butyrophilin, subfamily 3, member A2
C1ORF95 chromosome 1 open reading frame 95
C3AR1 complement component 3a receptor 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD247 CD247 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CUX2 cut-like homeobox 2
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FOSL2 FOS-like antigen 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HMX1 H6 family homeobox 1
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
ING2 inhibitor of growth family, member 2
KRT32 keratin 32, type I
LAMC2 laminin, gamma 2
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MED25 mediator complex subunit 25
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOG myelin oligodendrocyte glycoprotein
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYRF myelin regulatory factor
N4BP1 NEDD4 binding protein 1
NCAM1 neural cell adhesion molecule 1
NEB nebulin
NME5 NME/NM23 family member 5
NNMT nicotinamide N-methyltransferase
NPPA natriuretic peptide A
NUP214 nucleoporin 214kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PARP3 poly (ADP-ribose) polymerase family, member 3
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4DIP phosphodiesterase 4D interacting protein
PER1 period circadian clock 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGLYRP1 peptidoglycan recognition protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAT plasminogen activator, tissue
PLCL2 phospholipase C-like 2
PML promyelocytic leukemia
POU2F2 POU class 2 homeobox 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRB3 proline-rich protein BstNI subfamily 3
PRKCI protein kinase C, iota
PROSC proline synthetase co-transcribed homolog (bacterial)
PRR5 proline rich 5 (renal)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB33A RAB33A, member RAS oncogene family
RNF43 ring finger protein 43
RPL10 ribosomal protein L10
RPL18 ribosomal protein L18
RPL35A ribosomal protein L35a
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A14 solute carrier family 22, member 14
SNAI2 snail family zinc finger 2
SP110 SP110 nuclear body protein
SPP1 secreted phosphoprotein 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
T T, brachyury homolog (mouse)
TAPBP TAP binding protein (tapasin)
TBXA2R thromboxane A2 receptor
THPO thrombopoietin
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNIK TRAF2 and NCK interacting kinase
TYMS thymidylate synthetase
WTAP Wilms tumor 1 associated protein
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ART1 ADP-ribosyltransferase 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5 complement component 5
CCDC106 coiled-coil domain containing 106
CDK6 cyclin-dependent kinase 6
CFAP45 cilia and flagella associated protein 45
CPED1 cadherin-like and PC-esterase domain containing 1
CRY2 cryptochrome circadian clock 2
CSF1R colony stimulating factor 1 receptor
CTSF cathepsin F
CYB5R2 cytochrome b5 reductase 2
DDN dendrin
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4A DENN/MADD domain containing 4A
DNAL4 dynein, axonemal, light chain 4
DTX2 deltex 2, E3 ubiquitin ligase
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM204A family with sequence similarity 204, member A
FGF23 fibroblast growth factor 23
FKBP10 FK506 binding protein 10, 65 kDa
FMOD fibromodulin
GAN gigaxonin
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H1D histone cluster 1, H1d
HIST1H2BJ histone cluster 1, H2bj
HIST1H3G histone cluster 1, H3g
HOXC5 homeobox C5
IL1B interleukin 1, beta
INO80D INO80 complex subunit D
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0232 KIAA0232
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT15 keratin 15, type I
KRT9 keratin 9, type I
LAX1 lymphocyte transmembrane adaptor 1
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LOC390998 ribosomal protein L10 pseudogene
LPAR6 lysophosphatidic acid receptor 6
LRP2 low density lipoprotein receptor-related protein 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD1 LY6/PLAUR domain containing 1
MCC mutated in colorectal cancers
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF4 mitochondrial transcription termination factor 4
MUM1 melanoma associated antigen (mutated) 1
MXRA8 matrix-remodelling associated 8
NTSR1 neurotensin receptor 1 (high affinity)
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDH17 protocadherin 17
PDE12 phosphodiesterase 12
PHEX phosphate regulating endopeptidase homolog, X-linked
PMCH pro-melanin-concentrating hormone
PODXL2 podocalyxin-like 2
POU3F2 POU class 3 homeobox 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRAMEF11 PRAME family member 11
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRAGB Ras-related GTP binding B
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SIRT2 sirtuin 2
SLC25A40 solute carrier family 25, member 40
SLC46A3 solute carrier family 46, member 3
SMAD7 SMAD family member 7
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SND1-IT1 SND1 intronic transcript 1
SNTG1 syntrophin, gamma 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBX19 T-box 19
THRB thyroid hormone receptor, beta
TMC7 transmembrane channel-like 7
TMEM121 transmembrane protein 121
TMEM212 transmembrane protein 212
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOM1 target of myb1 (chicken)
TOR4A torsin family 4, member A
TPCN1 two pore segment channel 1
UGT8 UDP glycosyltransferase 8
VEZT vezatin, adherens junctions transmembrane protein
ZBTB6 zinc finger and BTB domain containing 6
ZNF324 zinc finger protein 324
ZNF41 zinc finger protein 41
ZNF428 zinc finger protein 428
ZNF492 zinc finger protein 492
ZNF862 zinc finger protein 862