| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the dexamethasone-5797 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ACAN | aggrecan |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| AGRN | agrin |
| ANGPTL4 | angiopoietin-like 4 |
| ANK2 | ankyrin 2, neuronal |
| ANXA10 | annexin A10 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP10A | ATPase, class V, type 10A |
| ATP9A | ATPase, class II, type 9A |
| ATXN7L1 | ataxin 7-like 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C3AR1 | complement component 3a receptor 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD247 | CD247 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CUX2 | cut-like homeobox 2 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| DRD2 | dopamine receptor D2 |
| DUSP1 | dual specificity phosphatase 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FOSL2 | FOS-like antigen 2 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HMX1 | H6 family homeobox 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| ING2 | inhibitor of growth family, member 2 |
| KRT32 | keratin 32, type I |
| LAMC2 | laminin, gamma 2 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MED25 | mediator complex subunit 25 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MOG | myelin oligodendrocyte glycoprotein |
| MX1 | MX dynamin-like GTPase 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MYRF | myelin regulatory factor |
| N4BP1 | NEDD4 binding protein 1 |
| NCAM1 | neural cell adhesion molecule 1 |
| NEB | nebulin |
| NME5 | NME/NM23 family member 5 |
| NNMT | nicotinamide N-methyltransferase |
| NPPA | natriuretic peptide A |
| NUP214 | nucleoporin 214kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PER1 | period circadian clock 1 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAT | plasminogen activator, tissue |
| PLCL2 | phospholipase C-like 2 |
| PML | promyelocytic leukemia |
| POU2F2 | POU class 2 homeobox 2 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKCI | protein kinase C, iota |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PRR5 | proline rich 5 (renal) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB33A | RAB33A, member RAS oncogene family |
| RNF43 | ring finger protein 43 |
| RPL10 | ribosomal protein L10 |
| RPL18 | ribosomal protein L18 |
| RPL35A | ribosomal protein L35a |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SNAI2 | snail family zinc finger 2 |
| SP110 | SP110 nuclear body protein |
| SPP1 | secreted phosphoprotein 1 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| T | T, brachyury homolog (mouse) |
| TAPBP | TAP binding protein (tapasin) |
| TBXA2R | thromboxane A2 receptor |
| THPO | thrombopoietin |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNIK | TRAF2 and NCK interacting kinase |
| TYMS | thymidylate synthetase |
| WTAP | Wilms tumor 1 associated protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ART1 | ADP-ribosyltransferase 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C5 | complement component 5 |
| CCDC106 | coiled-coil domain containing 106 |
| CDK6 | cyclin-dependent kinase 6 |
| CFAP45 | cilia and flagella associated protein 45 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSF1R | colony stimulating factor 1 receptor |
| CTSF | cathepsin F |
| CYB5R2 | cytochrome b5 reductase 2 |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAL4 | dynein, axonemal, light chain 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM204A | family with sequence similarity 204, member A |
| FGF23 | fibroblast growth factor 23 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FMOD | fibromodulin |
| GAN | gigaxonin |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3G | histone cluster 1, H3g |
| HOXC5 | homeobox C5 |
| IL1B | interleukin 1, beta |
| INO80D | INO80 complex subunit D |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0232 | KIAA0232 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT15 | keratin 15, type I |
| KRT9 | keratin 9, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LINS | lines homolog (Drosophila) |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MCC | mutated in colorectal cancers |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PCDH17 | protocadherin 17 |
| PDE12 | phosphodiesterase 12 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PMCH | pro-melanin-concentrating hormone |
| PODXL2 | podocalyxin-like 2 |
| POU3F2 | POU class 3 homeobox 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAMEF11 | PRAME family member 11 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RRAGB | Ras-related GTP binding B |
| SCG2 | secretogranin II |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SIRT2 | sirtuin 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMAD7 | SMAD family member 7 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNTG1 | syntrophin, gamma 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBX19 | T-box 19 |
| THRB | thyroid hormone receptor, beta |
| TMC7 | transmembrane channel-like 7 |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOM1 | target of myb1 (chicken) |
| TOR4A | torsin family 4, member A |
| TPCN1 | two pore segment channel 1 |
| UGT8 | UDP glycosyltransferase 8 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF324 | zinc finger protein 324 |
| ZNF41 | zinc finger protein 41 |
| ZNF428 | zinc finger protein 428 |
| ZNF492 | zinc finger protein 492 |
| ZNF862 | zinc finger protein 862 |