| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the dexibuprofen-3094 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BRS3 | bombesin-like receptor 3 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CD47 | CD47 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| COL7A1 | collagen, type VII, alpha 1 |
| DESI2 | desumoylating isopeptidase 2 |
| DICER1 | dicer 1, ribonuclease type III |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DPEP2 | dipeptidase 2 |
| DVL2 | dishevelled segment polarity protein 2 |
| EEA1 | early endosome antigen 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM46C | family with sequence similarity 46, member C |
| FAM65A | family with sequence similarity 65, member A |
| FAS | Fas cell surface death receptor |
| FASTK | Fas-activated serine/threonine kinase |
| FBXO22 | F-box protein 22 |
| FBXO31 | F-box protein 31 |
| FCF1 | FCF1 rRNA-processing protein |
| FOXO1 | forkhead box O1 |
| FST | follistatin |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLCE | glucuronic acid epimerase |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPX2 | glutathione peroxidase 2 |
| IFITM1 | interferon induced transmembrane protein 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KHK | ketohexokinase (fructokinase) |
| KRT8P12 | keratin 8 pseudogene 12 |
| LDB1 | LIM domain binding 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MNMIP1 | manchette microtubule inner protein 1 |
| MPZL1 | myelin protein zero-like 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYO1B | myosin IB |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NENF | neudesin neurotrophic factor |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OLFML2A | olfactomedin-like 2A |
| PENK | proenkephalin |
| PIGR | polymeric immunoglobulin receptor |
| PLCL2 | phospholipase C-like 2 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| POU2F2 | POU class 2 homeobox 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKY | protein kinase, Y-linked, pseudogene |
| PURG | purine-rich element binding protein G |
| PVR | poliovirus receptor |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RELN | reelin |
| RPL35A | ribosomal protein L35a |
| RPL7 | ribosomal protein L7 |
| RPS28 | ribosomal protein S28 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SMTN | smoothelin |
| SNTG1 | syntrophin, gamma 1 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STOM | stomatin |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBCD | tubulin folding cofactor D |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THRB | thyroid hormone receptor, beta |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TRIM3 | tripartite motif containing 3 |
| VSNL1 | visinin-like 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF235 | zinc finger protein 235 |
| ZNF528 | zinc finger protein 528 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ANO10 | anoctamin 10 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BEND5 | BEN domain containing 5 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C5AR1 | complement component 5a receptor 1 |
| CCDC106 | coiled-coil domain containing 106 |
| CDO1 | cysteine dioxygenase type 1 |
| CEP170B | centrosomal protein 170B |
| CEP97 | centrosomal protein 97kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLCA1 | chloride channel accessory 1 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CRYL1 | crystallin, lambda 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DUSP8 | dual specificity phosphatase 8 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| FAM13C | family with sequence similarity 13, member C |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FCHO1 | FCH domain only 1 |
| FES | FES proto-oncogene, tyrosine kinase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR27 | G protein-coupled receptor 27 |
| GPR35 | G protein-coupled receptor 35 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAMP | hepcidin antimicrobial peptide |
| HDAC7 | histone deacetylase 7 |
| HIST1H4E | histone cluster 1, H4e |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFNA14 | interferon, alpha 14 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| IRS1 | insulin receptor substrate 1 |
| JAM2 | junctional adhesion molecule 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIF24 | kinesin family member 24 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LOXL3 | lysyl oxidase-like 3 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP1S | microtubule-associated protein 1S |
| MDFI | MyoD family inhibitor |
| MYL5 | myosin, light chain 5, regulatory |
| NDE1 | nudE neurodevelopment protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDGFD | platelet derived growth factor D |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POR | P450 (cytochrome) oxidoreductase |
| POU5F1B | POU class 5 homeobox 1B |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROL1 | proline rich, lacrimal 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB17 | RAB17, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| SETBP1 | SET binding protein 1 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPHK1 | sphingosine kinase 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC5 | transmembrane channel-like 5 |
| TMEM120B | transmembrane protein 120B |
| TMEM180 | transmembrane protein 180 |
| TMEM246 | transmembrane protein 246 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| UNC119 | unc-119 homolog (C. elegans) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WASF3 | WAS protein family, member 3 |
| YY2 | YY2 transcription factor |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF862 | zinc finger protein 862 |