dexibuprofen-5311 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the dexibuprofen-5311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGAP4 Rho GTPase activating protein 4
ATP9A ATPase, class II, type 9A
ATXN2L ataxin 2-like
BCL9 B-cell CLL/lymphoma 9
BLNK B-cell linker
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CD44 CD44 molecule (Indian blood group)
CES3 carboxylesterase 3
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRY2 cryptochrome circadian clock 2
CTNS cystinosin, lysosomal cystine transporter
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EML3 echinoderm microtubule associated protein like 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EWSR1 EWS RNA-binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM149B1 family with sequence similarity 149, member B1
FBXL6 F-box and leucine-rich repeat protein 6
FCHO1 FCH domain only 1
FKBP8 FK506 binding protein 8, 38kDa
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GREB1 growth regulation by estrogen in breast cancer 1
GUK1 guanylate kinase 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST1H4D histone cluster 1, H4d
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNMT histamine N-methyltransferase
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSF1 heat shock transcription factor 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM4C lysine (K)-specific demethylase 4C
KLHL24 kelch-like family member 24
LAMP1 lysosomal-associated membrane protein 1
LOC647070 uncharacterized LOC647070
LPPR2 lipid phosphate phosphatase-related protein type 2
LRP5L low density lipoprotein receptor-related protein 5-like
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYRM9 LYR motif containing 9
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MFGE8 milk fat globule-EGF factor 8 protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MRPL41 mitochondrial ribosomal protein L41
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MXD3 MAX dimerization protein 3
MZF1 myeloid zinc finger 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAOX polyamine oxidase (exo-N4-amino)
PDE4DIP phosphodiesterase 4D interacting protein
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASAL1 RAS protein activator like 1 (GAP1 like)
RGS14 regulator of G-protein signaling 14
RNF126P1 ring finger protein 126 pseudogene 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10 ribosomal protein L10
RPL7 ribosomal protein L7
RPS4Y1 ribosomal protein S4, Y-linked 1
SAPCD1 suppressor APC domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRT3 sirtuin 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPAG8 sperm associated antigen 8
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRSF1 serine/arginine-rich splicing factor 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TAT tyrosine aminotransferase
TAZ tafazzin
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRIM66 tripartite motif containing 66
TSPAN31 tetraspanin 31
UHRF1BP1L UHRF1 binding protein 1-like
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR25 WD repeat domain 25
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF286A zinc finger protein 286A
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMC7 armadillo repeat containing 7
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BATF basic leucine zipper transcription factor, ATF-like
BCORL1 BCL6 corepressor-like 1
BIN3 bridging integrator 3
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
CCDC186 coiled-coil domain containing 186
CCDC94 coiled-coil domain containing 94
CCNL2 cyclin L2
CCNT1 cyclin T1
CDK11A cyclin-dependent kinase 11A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CMTR1 cap methyltransferase 1
COMMD9 COMM domain containing 9
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF17 DDB1 and CUL4 associated factor 17
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNMBP dynamin binding protein
EDC3 enhancer of mRNA decapping 3
EFHD1 EF-hand domain family, member D1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
EVPL envoplakin
EYA2 EYA transcriptional coactivator and phosphatase 2
FA2H fatty acid 2-hydroxylase
FAM86B1 family with sequence similarity 86, member B1
FBXL4 F-box and leucine-rich repeat protein 4
FOXC1 forkhead box C1
GAR1 GAR1 ribonucleoprotein
GCHFR GTP cyclohydrolase I feedback regulator
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR137B G protein-coupled receptor 137B
HMGB3P1 high mobility group box 3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
IFI6 interferon, alpha-inducible protein 6
IMPACT impact RWD domain protein
IRF9 interferon regulatory factor 9
KIAA0894 KIAA0894 protein
KIF18B kinesin family member 18B
KRI1 KRI1 homolog (S. cerevisiae)
LARS leucyl-tRNA synthetase
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
MB myoglobin
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED22 mediator complex subunit 22
MTCL1 microtubule crosslinking factor 1
MXRA7 matrix-remodelling associated 7
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUPL2 nucleoporin like 2
OCEL1 occludin/ELL domain containing 1
OPN3 opsin 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI2 peptidyl arginine deiminase, type II
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
RAB23 RAB23, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RNF219 ring finger protein 219
RNMTL1 RNA methyltransferase like 1
RRAGA Ras-related GTP binding A
RSAD1 radical S-adenosyl methionine domain containing 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC46A3 solute carrier family 46, member 3
SND1-IT1 SND1 intronic transcript 1
SNIP1 Smad nuclear interacting protein 1
SNX6 sorting nexin 6
SRBD1 S1 RNA binding domain 1
SSBP3 single stranded DNA binding protein 3
TBC1D16 TBC1 domain family, member 16
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TESK1 testis-specific kinase 1
TESK2 testis-specific kinase 2
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM184C transmembrane protein 184C
TOLLIP toll interacting protein
TRABD TraB domain containing
TRIP10 thyroid hormone receptor interactor 10
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTC17 tetratricopeptide repeat domain 17
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP18 ubiquitin specific peptidase 18
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WLS wntless Wnt ligand secretion mediator
ZBED1 zinc finger, BED-type containing 1
ZNF250 zinc finger protein 250