dexpanthenol-1680 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dexpanthenol-1680 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AKR1C2 aldo-keto reductase family 1, member C2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP44 Rho GTPase activating protein 44
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARSB arylsulfatase B
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B9D1 B9 protein domain 1
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
C19ORF66 chromosome 19 open reading frame 66
C19ORF73 chromosome 19 open reading frame 73
C21ORF2 chromosome 21 open reading frame 2
CDK18 cyclin-dependent kinase 18
COMT catechol-O-methyltransferase
CORT cortistatin
CUL7 cullin 7
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
E2F4 E2F transcription factor 4, p107/p130-binding
EMID1 EMI domain containing 1
EPS8L1 EPS8-like 1
EXOC7 exocyst complex component 7
FAS Fas cell surface death receptor
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLRX glutaredoxin (thioltransferase)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HN1L hematological and neurological expressed 1-like
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
IDI2-AS1 IDI2 antisense RNA 1
INO80D INO80 complex subunit D
KAT6A K(lysine) acetyltransferase 6A
KCNK12 potassium channel, two pore domain subfamily K, member 12
LARP7 La ribonucleoprotein domain family, member 7
LIG3 ligase III, DNA, ATP-dependent
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LOC644450 uncharacterized LOC644450
LY6D lymphocyte antigen 6 complex, locus D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MXRA8 matrix-remodelling associated 8
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFYA nuclear transcription factor Y, alpha
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAOX polyamine oxidase (exo-N4-amino)
PCDHA6 protocadherin alpha 6
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMP22 peripheral myelin protein 22
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTGES prostaglandin E synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB28 RAB28, member RAS oncogene family
RAD51B RAD51 paralog B
RGS10 regulator of G-protein signaling 10
RGS14 regulator of G-protein signaling 14
RNF126P1 ring finger protein 126 pseudogene 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SENP7 SUMO1/sentrin specific peptidase 7
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGSH N-sulfoglucosamine sulfohydrolase
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPRR1B small proline-rich protein 1B
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAT1 signal transducer and activator of transcription 1, 91kDa
STK16 serine/threonine kinase 16
STK17B serine/threonine kinase 17b
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SYNJ1 synaptojanin 1
TADA2A transcriptional adaptor 2A
TBX10 T-box 10
TTC9 tetratricopeptide repeat domain 9
TTLL1 tubulin tyrosine ligase-like family member 1
TTLL5 tubulin tyrosine ligase-like family member 5
TXNL4A thioredoxin-like 4A
UBOX5 U-box domain containing 5
USB1 U6 snRNA biogenesis 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
ALS2CL ALS2 C-terminal like
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BAHD1 bromo adjacent homology domain containing 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C19ORF40 chromosome 19 open reading frame 40
C7ORF43 chromosome 7 open reading frame 43
CBX7 chromobox homolog 7
CCNO cyclin O
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKD diacylglycerol kinase, delta 130kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNA3 ephrin-A3
EHD4 EH-domain containing 4
FAAH fatty acid amide hydrolase
FAM86C1 family with sequence similarity 86, member C1
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLCN folliculin
FLJ22184
FLT4 fms-related tyrosine kinase 4
GALT galactose-1-phosphate uridylyltransferase
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HECA headcase homolog (Drosophila)
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AJ histone cluster 1, H2aj
IFT22 intraflagellar transport 22
IRF9 interferon regulatory factor 9
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
LOC100272216 uncharacterized LOC100272216
LRRC8E leucine rich repeat containing 8 family, member E
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP9 microtubule-associated protein 9
MB myoglobin
MBTD1 mbt domain containing 1
METTL2B methyltransferase like 2B
NARFL nuclear prelamin A recognition factor-like
NIPAL2 NIPA-like domain containing 2
NLK nemo-like kinase
NRGN neurogranin (protein kinase C substrate, RC3)
NT5C 5', 3'-nucleotidase, cytosolic
PADI2 peptidyl arginine deiminase, type II
PCDHB3 protocadherin beta 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PILRB paired immunoglobin-like type 2 receptor beta
PLD2 phospholipase D2
PMEPA1 prostate transmembrane protein, androgen induced 1
PRSS22 protease, serine, 22
PSKH1 protein serine kinase H1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM23 RNA binding motif protein 23
RIC8B RIC8 guanine nucleotide exchange factor B
SHPK sedoheptulokinase
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA21 small nucleolar RNA, H/ACA box 21
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK25 serine/threonine kinase 25
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TLN1 talin 1
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TMEM184C transmembrane protein 184C
TRAPPC2 trafficking protein particle complex 2
TRIM66 tripartite motif containing 66
TSPAN14 tetraspanin 14
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBTF upstream binding transcription factor, RNA polymerase I
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VASH1 vasohibin 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WBP2 WW domain binding protein 2
WDR60 WD repeat domain 60
WDR7 WD repeat domain 7
WDR91 WD repeat domain 91
ZFAND3 zinc finger, AN1-type domain 3
ZFP30 ZFP30 zinc finger protein
ZMAT5 zinc finger, matrin-type 5
ZMYM3 zinc finger, MYM-type 3
ZNF205 zinc finger protein 205
ZNF580 zinc finger protein 580
ZNF652 zinc finger protein 652
ZSCAN31 zinc finger and SCAN domain containing 31