dexpanthenol-1802 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dexpanthenol-1802 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANOS1 anosmin 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APOE apolipoprotein E
ARFIP1 ADP-ribosylation factor interacting protein 1
ASPH aspartate beta-hydroxylase
BAHCC1 BAH domain and coiled-coil containing 1
BBS4 Bardet-Biedl syndrome 4
BNC1 basonuclin 1
CAPN2 calpain 2, (m/II) large subunit
CD70 CD70 molecule
CENPO centromere protein O
CHD1L chromodomain helicase DNA binding protein 1-like
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPD carboxypeptidase D
CREB1 cAMP responsive element binding protein 1
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CUL4A cullin 4A
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBT dihydrolipoamide branched chain transacylase E2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DOK4 docking protein 4
E2F5 E2F transcription factor 5, p130-binding
ECE1 endothelin converting enzyme 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHB2 EPH receptor B2
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FDX1 ferredoxin 1
FEM1C fem-1 homolog c (C. elegans)
FKBP10 FK506 binding protein 10, 65 kDa
FMR1 fragile X mental retardation 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLRX glutaredoxin (thioltransferase)
GNAS GNAS complex locus
GPR137 G protein-coupled receptor 137
HOOK1 hook microtubule-tethering protein 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL1RAP interleukin 1 receptor accessory protein
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIAA0319L KIAA0319-like
LINC00341 long intergenic non-protein coding RNA 341
LMAN1 lectin, mannose-binding, 1
MARS methionyl-tRNA synthetase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM4 minichromosome maintenance complex component 4
MED18 mediator complex subunit 18
MTAP methylthioadenosine phosphorylase
MVK mevalonate kinase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFIB nuclear factor I/B
NNT nicotinamide nucleotide transhydrogenase
NOTCH2 notch 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
ORC4 origin recognition complex, subunit 4
PALMD palmdelphin
PCNX pecanex homolog (Drosophila)
PDLIM5 PDZ and LIM domain 5
PEX11A peroxisomal biogenesis factor 11 alpha
PHACTR4 phosphatase and actin regulator 4
PHF7 PHD finger protein 7
PML promyelocytic leukemia
PRR15L proline rich 15-like
PSAT1 phosphoserine aminotransferase 1
PSD3 pleckstrin and Sec7 domain containing 3
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXMP4 peroxisomal membrane protein 4, 24kDa
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP2 RNA polymerase II associated protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
SCAPER S-phase cyclin A-associated protein in the ER
SCNN1B sodium channel, non voltage gated 1 beta subunit
SETD6 SET domain containing 6
SGPP1 sphingosine-1-phosphate phosphatase 1
SIDT2 SID1 transmembrane family, member 2
SIRPA signal-regulatory protein alpha
SLC25A44 solute carrier family 25, member 44
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC1A structural maintenance of chromosomes 1A
SPTAN1 spectrin, alpha, non-erythrocytic 1
SS18 synovial sarcoma translocation, chromosome 18
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TCF4 transcription factor 4
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPD52L1 tumor protein D52-like 1
TUSC2 tumor suppressor candidate 2
UBOX5 U-box domain containing 5
UBQLN4 ubiquilin 4
UTRN utrophin
WRAP53 WD repeat containing, antisense to TP53
YPEL1 yippee-like 1 (Drosophila)
ZER1 zyg-11 related, cell cycle regulator
ZFP30 ZFP30 zinc finger protein
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTG2 actin, gamma 2, smooth muscle, enteric
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARF5 ADP-ribosylation factor 5
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BDNF brain-derived neurotrophic factor
BTBD2 BTB (POZ) domain containing 2
C1QTNF1 C1q and tumor necrosis factor related protein 1
C8ORF60 chromosome 8 open reading frame 60
CCDC69 coiled-coil domain containing 69
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COPS7B COP9 signalosome subunit 7B
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND4B DENN/MADD domain containing 4B
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHRS9 dehydrogenase/reductase (SDR family) member 9
DMBT1 deleted in malignant brain tumors 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAL4 dynein, axonemal, light chain 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
FAM155A family with sequence similarity 155, member A
FAM206A family with sequence similarity 206, member A
FAM50B family with sequence similarity 50, member B
FAM53B family with sequence similarity 53, member B
FKBPL FK506 binding protein like
FOXC1 forkhead box C1
FPGS folylpolyglutamate synthase
FUZ fuzzy planar cell polarity protein
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR1 G protein-coupled receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
JAM3 junctional adhesion molecule 3
LIMS2 LIM and senescent cell antigen-like domains 2
LZTR1 leucine-zipper-like transcription regulator 1
MAGEA3 melanoma antigen family A3
MANBA mannosidase, beta A, lysosomal
MANSC1 MANSC domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK12 mitogen-activated protein kinase 12
MCMBP minichromosome maintenance complex binding protein
MEIS3P1 Meis homeobox 3 pseudogene 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MRPL52 mitochondrial ribosomal protein L52
MRPS34 mitochondrial ribosomal protein S34
MX1 MX dynamin-like GTPase 1
MYL5 myosin, light chain 5, regulatory
NOL6 nucleolar protein 6 (RNA-associated)
NR1H3 nuclear receptor subfamily 1, group H, member 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCOLCE procollagen C-endopeptidase enhancer
PEX13 peroxisomal biogenesis factor 13
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RAD54L2 RAD54-like 2 (S. cerevisiae)
RARS arginyl-tRNA synthetase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
RUSC2 RUN and SH3 domain containing 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT2 sirtuin 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMA4 glucuronidase, beta pseudogene
SND1-IT1 SND1 intronic transcript 1
SNHG20 small nucleolar RNA host gene 20
SNX15 sorting nexin 15
STX1A syntaxin 1A (brain)
SYT17 synaptotagmin XVII
TCTN1 tectonic family member 1
TGFBR3 transforming growth factor, beta receptor III
TGS1 trimethylguanosine synthase 1
TMEM104 transmembrane protein 104
TMEM242 transmembrane protein 242
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNRC6B trinucleotide repeat containing 6B
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC22D4 TSC22 domain family, member 4
TUBG2 tubulin, gamma 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
YEATS2 YEATS domain containing 2
ZC3H12A zinc finger CCCH-type containing 12A
ZNF232 zinc finger protein 232
ZSCAN16 zinc finger and SCAN domain containing 16