dexpropranolol-3553 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dexpropranolol-3553 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANXA2P1 annexin A2 pseudogene 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATAT1 alpha tubulin acetyltransferase 1
ATF7IP activating transcription factor 7 interacting protein
ATP10B ATPase, class V, type 10B
BGN biglycan
BIN1 bridging integrator 1
BMP5 bone morphogenetic protein 5
C1ORF54 chromosome 1 open reading frame 54
C1QTNF1 C1q and tumor necrosis factor related protein 1
CA5B carbonic anhydrase VB, mitochondrial
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CALD1 caldesmon 1
CCKAR cholecystokinin A receptor
CCPG1 cell cycle progression 1
CD22 CD22 molecule
CLCN6 chloride channel, voltage-sensitive 6
CLIC2 chloride intracellular channel 2
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CSHL1 chorionic somatomammotropin hormone-like 1
CTIF CBP80/20-dependent translation initiation factor
CYLD cylindromatosis (turban tumor syndrome)
DDN dendrin
DEPDC5 DEP domain containing 5
DICER1 dicer 1, ribonuclease type III
DKFZP434L187 uncharacterized LOC26082
DMPK dystrophia myotonica-protein kinase
DMXL2 Dmx-like 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPX eosinophil peroxidase
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETNK2 ethanolamine kinase 2
EVA1B eva-1 homolog B (C. elegans)
EXT1 exostosin glycosyltransferase 1
FBXO9 F-box protein 9
FGFR3 fibroblast growth factor receptor 3
GNAS GNAS complex locus
GRM2 glutamate receptor, metabotropic 2
HOMER3 homer scaffolding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
ITGA8 integrin, alpha 8
ITGB6 integrin, beta 6
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LIPE lipase, hormone-sensitive
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYST lysosomal trafficking regulator
MAGEC3 melanoma antigen family C3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR7 myotubularin related protein 7
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOF myoferlin
NDRG2 NDRG family member 2
NOL10 nucleolar protein 10
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDCD3 NudC domain containing 3
NUP214 nucleoporin 214kDa
NUP88 nucleoporin 88kDa
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
PCDHA6 protocadherin alpha 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE9A phosphodiesterase 9A
PICK1 protein interacting with PRKCA 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G5 phospholipase A2, group V
POU6F1 POU class 6 homeobox 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRAMEF11 PRAME family member 11
PRND prion protein 2 (dublet)
PSG4 pregnancy specific beta-1-glycoprotein 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A2 S100 calcium binding protein A2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD1 SMAD family member 1
SPARCL1 SPARC-like 1 (hevin)
SPRR1A small proline-rich protein 1A
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN5 spectrin, beta, non-erythrocytic 5
STC1 stanniocalcin 1
STK11 serine/threonine kinase 11
STK24 serine/threonine kinase 24
TBC1D17 TBC1 domain family, member 17
TGFB2 transforming growth factor, beta 2
TPSG1 tryptase gamma 1
TUBA4B tubulin, alpha 4b
VPS9D1 VPS9 domain containing 1
WNT2B wingless-type MMTV integration site family, member 2B
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADM adrenomedullin
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB1 arrestin, beta 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BTBD7 BTB (POZ) domain containing 7
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
CCDC186 coiled-coil domain containing 186
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP85 centrosomal protein 85kDa
CFAP45 cilia and flagella associated protein 45
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST10 carbohydrate sulfotransferase 10
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLIC3 chloride intracellular channel 3
CNGB3 cyclic nucleotide gated channel beta 3
COL9A2 collagen, type IX, alpha 2
CPTP ceramide-1-phosphate transfer protein
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUEDC1 CUE domain containing 1
DDIT3 DNA-damage-inducible transcript 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP2 dual specificity phosphatase 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENO2 enolase 2 (gamma, neuronal)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAAH fatty acid amide hydrolase
FAM169A family with sequence similarity 169, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGF23 fibroblast growth factor 23
FGGY FGGY carbohydrate kinase domain containing
FOXN2 forkhead box N2
GMEB1 glucocorticoid modulatory element binding protein 1
GPX2 glutathione peroxidase 2
GSTA4 glutathione S-transferase alpha 4
GTF2I general transcription factor IIi
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
INCENP inner centromere protein antigens 135/155kDa
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
LOC390998 ribosomal protein L10 pseudogene
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTG1 mitochondrial ribosome-associated GTPase 1
MUM1 melanoma associated antigen (mutated) 1
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PLEK2 pleckstrin 2
PROS1 protein S (alpha)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS22 protease, serine, 22
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTK6 protein tyrosine kinase 6
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBL1 retinoblastoma-like 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL10L ribosomal protein L10-like
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A4 S100 calcium binding protein A4
SIX1 SIX homeobox 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
ST5 suppression of tumorigenicity 5
STAG3 stromal antigen 3
THBS3 thrombospondin 3
TLR5 toll-like receptor 5
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TOLLIP toll interacting protein
TPK1 thiamin pyrophosphokinase 1
TRAIP TRAF interacting protein
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
WDR4 WD repeat domain 4
WDR91 WD repeat domain 91
ZNF227 zinc finger protein 227
ZNF324 zinc finger protein 324
ZNF480 zinc finger protein 480
ZNF573 zinc finger protein 573
ZNF747 zinc finger protein 747