dexpropranolol-6130 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the dexpropranolol-6130 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACP5 acid phosphatase 5, tartrate resistant
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM12 ADAM metallopeptidase domain 12
ADAM22 ADAM metallopeptidase domain 22
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALOX5 arachidonate 5-lipoxygenase
APOL1 apolipoprotein L, 1
AQP7 aquaporin 7
AREG amphiregulin
ARR3 arrestin 3, retinal (X-arrestin)
AUTS2 autism susceptibility candidate 2
AVPR1B arginine vasopressin receptor 1B
C16ORF45 chromosome 16 open reading frame 45
C19ORF73 chromosome 19 open reading frame 73
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAV2 caveolin 2
CCDC85C coiled-coil domain containing 85C
CD160 CD160 molecule
CD1A CD1a molecule
CEND1 cell cycle exit and neuronal differentiation 1
CHGA chromogranin A
CNTD2 cyclin N-terminal domain containing 2
COL6A1 collagen, type VI, alpha 1
CRLF1 cytokine receptor-like factor 1
CRYBB1 crystallin, beta B1
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNA5 ephrin-A5
ESR1 estrogen receptor 1
FGF17 fibroblast growth factor 17
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GIPC2 GIPC PDZ domain containing family, member 2
GPC1 glypican 1
GUK1 guanylate kinase 1
HAB1 B1 for mucin
HLA-DOA major histocompatibility complex, class II, DO alpha
HNF4A hepatocyte nuclear factor 4, alpha
HR hair growth associated
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IGHM immunoglobulin heavy constant mu
IGSF3 immunoglobulin superfamily, member 3
IL17RC interleukin 17 receptor C
INPP5J inositol polyphosphate-5-phosphatase J
IQCG IQ motif containing G
KDM5B lysine (K)-specific demethylase 5B
KIAA1654 KIAA1654 protein
KLK11 kallikrein-related peptidase 11
LAMC3 laminin, gamma 3
LAMP3 lysosomal-associated membrane protein 3
LCAT lecithin-cholesterol acyltransferase
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MCAM melanoma cell adhesion molecule
MCF2L MCF.2 cell line derived transforming sequence-like
MLH3 mutL homolog 3
NF2 neurofibromin 2 (merlin)
NIPAL2 NIPA-like domain containing 2
PADI2 peptidyl arginine deiminase, type II
PALLD palladin, cytoskeletal associated protein
PCSK6 proprotein convertase subtilisin/kexin type 6
PLIN2 perilipin 2
POPDC2 popeye domain containing 2
POU2F2 POU class 2 homeobox 2
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB2A RAB2A, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RET ret proto-oncogene
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SECTM1 secreted and transmembrane 1
SELENBP1 selenium binding protein 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOCS3 suppressor of cytokine signaling 3
SOCS7 suppressor of cytokine signaling 7
SRPK3 SRSF protein kinase 3
ST7L suppression of tumorigenicity 7 like
SYCP1 synaptonemal complex protein 1
TCF20 transcription factor 20 (AR1)
TK2 thymidine kinase 2, mitochondrial
TNK2 tyrosine kinase, non-receptor, 2
TP53I11 tumor protein p53 inducible protein 11
TROVE2 TROVE domain family, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USB1 U6 snRNA biogenesis 1
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WDR55 WD repeat domain 55
WWOX WW domain containing oxidoreductase
ZNF280A zinc finger protein 280A
ZNF76 zinc finger protein 76
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACO1 aconitase 1, soluble
AGO1 argonaute RISC catalytic component 1
ALS2CL ALS2 C-terminal like
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA3 annexin A3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASB7 ankyrin repeat and SOCS box containing 7
BBS10 Bardet-Biedl syndrome 10
BIK BCL2-interacting killer (apoptosis-inducing)
BRD1 bromodomain containing 1
BST1 bone marrow stromal cell antigen 1
C5AR1 complement component 5a receptor 1
CD1D CD1d molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CEP131 centrosomal protein 131kDa
CHM choroideremia (Rab escort protein 1)
CRYZ crystallin, zeta (quinone reductase)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DOCK4 dedicator of cytokinesis 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM127B family with sequence similarity 127, member B
FHOD1 formin homology 2 domain containing 1
FJX1 four jointed box 1 (Drosophila)
G6PD glucose-6-phosphate dehydrogenase
GCHFR GTP cyclohydrolase I feedback regulator
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AE histone cluster 1, H2ae
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
INO80D INO80 complex subunit D
KAT2A K(lysine) acetyltransferase 2A
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
MED18 mediator complex subunit 18
METRN meteorin, glial cell differentiation regulator
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MINPP1 multiple inositol-polyphosphate phosphatase 1
MOCOS molybdenum cofactor sulfurase
MYL5 myosin, light chain 5, regulatory
NCKAP1L NCK-associated protein 1-like
NOD2 nucleotide-binding oligomerization domain containing 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
ORC2 origin recognition complex, subunit 2
PAQR6 progestin and adipoQ receptor family member VI
PDIA3 protein disulfide isomerase family A, member 3
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR14L proline rich 14-like
PYGB phosphorylase, glycogen; brain
RBM41 RNA binding motif protein 41
RFXAP regulatory factor X-associated protein
RINT1 RAD50 interactor 1
RNF122 ring finger protein 122
RNF141 ring finger protein 141
RUSC2 RUN and SH3 domain containing 2
SERGEF secretion regulating guanine nucleotide exchange factor
SETD1A SET domain containing 1A
SLC12A9 solute carrier family 12, member 9
SLC16A4 solute carrier family 16, member 4
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX16 sorting nexin 16
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TMEM254 transmembrane protein 254
TMOD3 tropomodulin 3 (ubiquitous)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRPS1 trichorhinophalangeal syndrome I
TTC26 tetratricopeptide repeat domain 26
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
YY2 YY2 transcription factor
ZHX2 zinc fingers and homeoboxes 2
ZMAT5 zinc finger, matrin-type 5
ZNF329 zinc finger protein 329
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF394 zinc finger protein 394