dgcr8 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	DGCR8 microprocessor complex subunit\|This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 54487)
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Genes

13 genes co-occuring with the biological term dgcr8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AGO1	argonaute RISC catalytic component 1
AGO2	argonaute RISC catalytic component 2
AURKB	aurora kinase B
DGCR8	DGCR8 microprocessor complex subunit
DROSHA	drosha, ribonuclease type III
HDAC1	histone deacetylase 1
MIR409	microRNA 409
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
SOX3	SRY (sex determining region Y)-box 3
SRY	sex determining region Y
TARBP1	TAR (HIV-1) RNA binding protein 1
TFCP2	transcription factor CP2
TP63	tumor protein p63