diabetes mellitus, type 2 Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
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129 genes associated with the disease diabetes mellitus, type 2 in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ADD1 adducin 1 (alpha)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANK1 ankyrin 1, erythrocytic
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOA5 apolipoprotein A-V
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP26 Rho GTPase activating protein 26
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C1ORF204 chromosome 1 open reading frame 204
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CMIP c-Maf inducing protein
CNBD1 cyclic nucleotide binding domain containing 1
CORO1C coronin, actin binding protein, 1C
CPT1B carnitine palmitoyltransferase 1B (muscle)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRTAC1 cartilage acidic protein 1
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DUSP12 dual specificity phosphatase 12
FFAR1 free fatty acid receptor 1
FGGY FGGY carbohydrate kinase domain containing
FTO fat mass and obesity associated
G6PC2 glucose-6-phosphatase, catalytic, 2
GAS2 growth arrest-specific 2
GCK glucokinase (hexokinase 4)
GLIS3 GLIS family zinc finger 3
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
HDAC9 histone deacetylase 9
HHEX hematopoietically expressed homeobox
HIGD1C HIG1 hypoxia inducible domain family, member 1C
HIPK2 homeodomain interacting protein kinase 2
HK1 hexokinase 1
HMG20A high mobility group 20A
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP1 insulin-like growth factor binding protein 1
IL18 interleukin 18
IL6 interleukin 6
INSR insulin receptor
JAZF1 JAZF zinc finger 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK16 potassium channel, two pore domain subfamily K, member 16
KCNK17 potassium channel, two pore domain subfamily K, member 17
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LEP leptin
LEPR leptin receptor
LPIN1 lipin 1
LPIN2 lipin 2
MADD MAP-kinase activating death domain
MAEA macrophage erythroblast attacher
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MAST4 microtubule associated serine/threonine kinase family member 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAMPT nicotinamide phosphoribosyltransferase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH2 notch 2
NRG1 neuregulin 1
OASL 2'-5'-oligoadenylate synthetase-like
PALM2 paralemmin 2
PAPL iron/zinc purple acid phosphatase-like protein
PCNXL2 pecanex-like 2 (Drosophila)
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PDZRN3 PDZ domain containing ring finger 3
PEPD peptidase D
PEX5L peroxisomal biogenesis factor 5-like
PINK1 PTEN induced putative kinase 1
PLB1 phospholipase B1
PLS1 plastin 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRC1 protein regulator of cytokinesis 1
PRKCA protein kinase C, alpha
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRM protein tyrosine phosphatase, receptor type, M
RBMS1 RNA binding motif, single stranded interacting protein 1
RETN resistin
RTL1 retrotransposon-like 1
RUNX2 runt-related transcription factor 2
SDHAF4 succinate dehydrogenase complex assembly factor 4
SETBP1 SET binding protein 1
SGSM2 small G protein signaling modulator 2
SH3BP4 SH3-domain binding protein 4
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC25A27 solute carrier family 25, member 27
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNX7 sorting nexin 7
SORCS2 sortilin-related VPS10 domain containing receptor 2
SRR serine racemase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SVIP small VCP/p97-interacting protein
SYK spleen tyrosine kinase
SYNE1 spectrin repeat containing, nuclear envelope 1
TCERG1L transcription elongation regulator 1-like
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THADA thyroid adenoma associated
TMEM108 transmembrane protein 108
TNF tumor necrosis factor
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPK1 thiamin pyrophosphokinase 1
TYK2 tyrosine kinase 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VSIG10 V-set and immunoglobulin domain containing 10
WFS1 Wolfram syndrome 1 (wolframin)
ZFAND3 zinc finger, AN1-type domain 3