| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | diablo, IAP-binding mitochondrial protein|This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 56616) |
| Similar Terms | |
| Downloads & Tools |
5 genes co-occuring with the biological term diablo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
