diarrhea Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A gastrointestinal system disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea. (Human Disease Ontology, DOID_13250)
Similar Terms
Downloads & Tools

Genes

44 genes co-occuring with the biological term diarrhea in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
APOE apolipoprotein E
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CD14 CD14 molecule
CD4 CD4 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CXCL8 chemokine (C-X-C motif) ligand 8
EGFR epidermal growth factor receptor
FGF19 fibroblast growth factor 19
FGFR4 fibroblast growth factor receptor 4
GNAS GNAS complex locus
GUCY2C guanylate cyclase 2C
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
IL10 interleukin 10
ISG20 interferon stimulated exonuclease gene 20kDa
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KLB klotho beta
LEP leptin
MT-ATP6 ATP synthase F0 subunit 6
MT-ATP8 ATP synthase F0 subunit 8
NEUROG3 neurogenin 3
PKM pyruvate kinase, muscle
PRNP prion protein
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
S100A9 S100 calcium binding protein A9
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STXBP2 syntaxin binding protein 2
TAC1 tachykinin, precursor 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TTC37 tetratricopeptide repeat domain 37
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1