diazoxide-1368 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the diazoxide-1368 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AGRN agrin
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APAF1 apoptotic peptidase activating factor 1
ARFRP1 ADP-ribosylation factor related protein 1
ARR3 arrestin 3, retinal (X-arrestin)
ASMTL acetylserotonin O-methyltransferase-like
ATG12 autophagy related 12
ATG13 autophagy related 13
ATXN2 ataxin 2
AVL9 AVL9 homolog (S. cerevisiase)
C1ORF109 chromosome 1 open reading frame 109
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CC2D1A coiled-coil and C2 domain containing 1A
CCPG1 cell cycle progression 1
CDK6 cyclin-dependent kinase 6
CEP152 centrosomal protein 152kDa
CEP170 centrosomal protein 170kDa
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPED1 cadherin-like and PC-esterase domain containing 1
CRAT carnitine O-acetyltransferase
DAZAP2 DAZ associated protein 2
DCAF8 DDB1 and CUL4 associated factor 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DSCR3 Down syndrome critical region 3
DTNA dystrobrevin, alpha
DVL3 dishevelled segment polarity protein 3
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELMO2 engulfment and cell motility 2
FASTK Fas-activated serine/threonine kinase
FGL2 fibrinogen-like 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FPR2 formyl peptide receptor 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPSM3 G-protein signaling modulator 3
GSK3A glycogen synthase kinase 3 alpha
GSTZ1 glutathione S-transferase zeta 1
HEATR3 HEAT repeat containing 3
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ITM2B integral membrane protein 2B
KRT18 keratin 18, type I
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIMD1 LIM domains containing 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST2 microtubule associated serine/threonine kinase 2
METTL7A methyltransferase like 7A
MGAM maltase-glucoamylase
MIS18BP1 MIS18 binding protein 1
MOB3B MOB kinase activator 3B
MRPS12 mitochondrial ribosomal protein S12
MYL10 myosin, light chain 10, regulatory
MYO1C myosin IC
NADK NAD kinase
NCR2 natural cytotoxicity triggering receptor 2
NELL2 NEL-like 2 (chicken)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NVL nuclear VCP-like
PAQR6 progestin and adipoQ receptor family member VI
PLEK2 pleckstrin 2
PNPLA4 patatin-like phospholipase domain containing 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRMT2IP PRMT2 interacting protein
PTX3 pentraxin 3, long
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
R3HDM1 R3H domain containing 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS1 regulator of G-protein signaling 1
RHOD ras homolog family member D
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SEC14L1 SEC14-like 1 (S. cerevisiae)
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SSH3 slingshot protein phosphatase 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAG3 stromal antigen 3
SUGP1 SURP and G patch domain containing 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCAF1 TRPM8 channel-associated factor 1
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM127 transmembrane protein 127
TMEM57 transmembrane protein 57
TMSB4Y thymosin beta 4, Y-linked
TRA T cell receptor alpha locus
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
WWC1 WW and C2 domain containing 1
XYLT1 xylosyltransferase I
ZNF337 zinc finger protein 337
ZNF747 zinc finger protein 747
ZNF783 zinc finger family member 783
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ABHD3 abhydrolase domain containing 3
ACO1 aconitase 1, soluble
ACOT13 acyl-CoA thioesterase 13
ACOT8 acyl-CoA thioesterase 8
ACVR2A activin A receptor, type IIA
ADAM15 ADAM metallopeptidase domain 15
ANKRD46 ankyrin repeat domain 46
ARGLU1 arginine and glutamate rich 1
ARHGAP4 Rho GTPase activating protein 4
BBS1 Bardet-Biedl syndrome 1
BCCIP BRCA2 and CDKN1A interacting protein
C19ORF54 chromosome 19 open reading frame 54
CALCOCO1 calcium binding and coiled-coil domain 1
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCNL2 cyclin L2
CENPC centromere protein C
CER1 cerberus 1, DAN family BMP antagonist
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CISH cytokine inducible SH2-containing protein
CMTR1 cap methyltransferase 1
COPS7B COP9 signalosome subunit 7B
CRIPT cysteine-rich PDZ-binding protein
CRYL1 crystallin, lambda 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DCTN6 dynactin 6
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK2 docking protein 2, 56kDa
EAPP E2F-associated phosphoprotein
ELSPBP1 epididymal sperm binding protein 1
ERO1L ERO1-like (S. cerevisiae)
EXTL2 exostosin-like glycosyltransferase 2
FAM172A family with sequence similarity 172, member A
GAA glucosidase, alpha; acid
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRWD1 glutamate-rich WD repeat containing 1
GSTA4 glutathione S-transferase alpha 4
GTPBP2 GTP binding protein 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL2RB interleukin 2 receptor, beta
INO80D INO80 complex subunit D
INTS9 integrator complex subunit 9
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD20 potassium channel tetramerization domain containing 20
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM5C lysine (K)-specific demethylase 5C
KPNA4 karyopherin alpha 4 (importin alpha 3)
LBR lamin B receptor
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LTN1 listerin E3 ubiquitin protein ligase 1
MED15 mediator complex subunit 15
METRN meteorin, glial cell differentiation regulator
MID1IP1 MID1 interacting protein 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRGBP MRG/MORF4L binding protein
NOD1 nucleotide-binding oligomerization domain containing 1
NOL6 nucleolar protein 6 (RNA-associated)
NR1D2 nuclear receptor subfamily 1, group D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PHACTR4 phosphatase and actin regulator 4
PMM2 phosphomannomutase 2
QPRT quinolinate phosphoribosyltransferase
RABL6 RAB, member RAS oncogene family-like 6
RBM47 RNA binding motif protein 47
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF113A ring finger protein 113A
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SETD1B SET domain containing 1B
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STEAP3 STEAP family member 3, metalloreductase
TAC3 tachykinin 3
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
TBL3 transducin (beta)-like 3
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRAPPC12 trafficking protein particle complex 12
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC1 tetratricopeptide repeat domain 1
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
XPA xeroderma pigmentosum, complementation group A
YIPF1 Yip1 domain family, member 1
ZNF408 zinc finger protein 408
ZXDC ZXD family zinc finger C