| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the diazoxide-2214 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP11A | ATPase, class VI, type 11A |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1QB | complement component 1, q subcomponent, B chain |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHM | choroideremia (Rab escort protein 1) |
| COL6A1 | collagen, type VI, alpha 1 |
| COMMD4 | COMM domain containing 4 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DLX2 | distal-less homeobox 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DOK2 | docking protein 2, 56kDa |
| EPHA5 | EPH receptor A5 |
| ETV5 | ets variant 5 |
| FGF16 | fibroblast growth factor 16 |
| FH | fumarate hydratase |
| FKRP | fukutin related protein |
| FRMD1 | FERM domain containing 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GIMAP6 | GTPase, IMAP family member 6 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LEFTY2 | left-right determination factor 2 |
| LPL | lipoprotein lipase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYL10 | myosin, light chain 10, regulatory |
| NF2 | neurofibromin 2 (merlin) |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NPAS3 | neuronal PAS domain protein 3 |
| NUP188 | nucleoporin 188kDa |
| OCLM | oculomedin |
| PCDHA5 | protocadherin alpha 5 |
| PCNX | pecanex homolog (Drosophila) |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POU4F2 | POU class 4 homeobox 2 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RIF1 | replication timing regulatory factor 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRPA | signal-regulatory protein alpha |
| SIRT5 | sirtuin 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMIM14 | small integral membrane protein 14 |
| SOAT2 | sterol O-acyltransferase 2 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRGN | serglycin |
| STX2 | syntaxin 2 |
| STX7 | syntaxin 7 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TLR5 | toll-like receptor 5 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TPSG1 | tryptase gamma 1 |
| TUBA3C | tubulin, alpha 3c |
| TUBBP5 | tubulin, beta pseudogene 5 |
| USP46 | ubiquitin specific peptidase 46 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AFAP1 | actin filament associated protein 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC71 | coiled-coil domain containing 71 |
| CD80 | CD80 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CEL | carboxyl ester lipase |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CERS4 | ceramide synthase 4 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DMTN | dematin actin binding protein |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FLCN | folliculin |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR157 | G protein-coupled receptor 157 |
| GPR21 | G protein-coupled receptor 21 |
| GRPR | gastrin-releasing peptide receptor |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTPBP2 | GTP binding protein 2 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4D | histone cluster 1, H4d |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA10 | integrin, alpha 10 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0355 | KIAA0355 |
| KIF13B | kinesin family member 13B |
| KLHL25 | kelch-like family member 25 |
| KLHL28 | kelch-like family member 28 |
| KRBOX4 | KRAB box domain containing 4 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MVP | major vault protein |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PICK1 | protein interacting with PRKCA 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLD3 | phospholipase D family, member 3 |
| PODNL1 | podocan-like 1 |
| PRKCE | protein kinase C, epsilon |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCAN3 | RCAN family member 3 |
| RIN2 | Ras and Rab interactor 2 |
| RNF170 | ring finger protein 170 |
| RNF2 | ring finger protein 2 |
| RNF208 | ring finger protein 208 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SDC3 | syndecan 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD1A | SET domain containing 1A |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SRPX | sushi-repeat containing protein, X-linked |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STIM1 | stromal interaction molecule 1 |
| TCTA | T-cell leukemia translocation altered |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TLR2 | toll-like receptor 2 |
| TMEM104 | transmembrane protein 104 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSPAN2 | tetraspanin 2 |
| TWF2 | twinfilin actin binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZIC3 | Zic family member 3 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
| ZNF611 | zinc finger protein 611 |
| ZNF623 | zinc finger protein 623 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |