diazoxide Gene Set

Dataset Guide to Pharmacology Chemical Ligands of Receptors
Category physical interactions
Type ligand (chemical)
Description A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. (Chemical Entities of Biological Interest Ontology, CHEBI_4495)
External Link http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=2409
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Genes

2 receptors of the diazoxide ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Symbol Name
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8