| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the diclofenac-2756 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| APOM | apolipoprotein M |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| CAPN5 | calpain 5 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CHI3L2 | chitinase 3-like 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| COL5A1 | collagen, type V, alpha 1 |
| COPA | coatomer protein complex, subunit alpha |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOK4 | docking protein 4 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DVL3 | dishevelled segment polarity protein 3 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EPX | eosinophil peroxidase |
| ETV7 | ets variant 7 |
| EWSR1 | EWS RNA-binding protein 1 |
| EXOSC1 | exosome component 1 |
| FAM214B | family with sequence similarity 214, member B |
| FER | fer (fps/fes related) tyrosine kinase |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GFER | growth factor, augmenter of liver regeneration |
| GMPR | guanosine monophosphate reductase |
| GPR22 | G protein-coupled receptor 22 |
| HLA-C | major histocompatibility complex, class I, C |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HOXC8 | homeobox C8 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFNA17 | interferon, alpha 17 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IHH | indian hedgehog |
| IQCK | IQ motif containing K |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF4 | interferon regulatory factor 4 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0319L | KIAA0319-like |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT75 | keratin 75, type II |
| LATS1 | large tumor suppressor kinase 1 |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MORN1 | MORN repeat containing 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MT3 | metallothionein 3 |
| MTMR7 | myotubularin related protein 7 |
| NCOA2 | nuclear receptor coactivator 2 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NME5 | NME/NM23 family member 5 |
| NUP188 | nucleoporin 188kDa |
| NUP50 | nucleoporin 50kDa |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDE10A | phosphodiesterase 10A |
| PLAU | plasminogen activator, urokinase |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPL35A | ribosomal protein L35a |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SH2B1 | SH2B adaptor protein 1 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TBX19 | T-box 19 |
| TBXA2R | thromboxane A2 receptor |
| TDRKH | tudor and KH domain containing |
| TEX40 | testis expressed 40 |
| THRB | thyroid hormone receptor, beta |
| TK2 | thymidine kinase 2, mitochondrial |
| TP63 | tumor protein p63 |
| TRIM29 | tripartite motif containing 29 |
| UPK3A | uroplakin 3A |
| VEGFA | vascular endothelial growth factor A |
| XDH | xanthine dehydrogenase |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AEN | apoptosis enhancing nuclease |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| CA11 | carbonic anhydrase XI |
| CCDC132 | coiled-coil domain containing 132 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHKB | choline kinase beta |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLDN15 | claudin 15 |
| CST6 | cystatin E/M |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM1 | dynamin 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELMO3 | engulfment and cell motility 3 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM188A | family with sequence similarity 188, member A |
| FBXO22 | F-box protein 22 |
| FGL1 | fibrinogen-like 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXN2 | forkhead box N2 |
| FPGS | folylpolyglutamate synthase |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GK3P | glycerol kinase 3 pseudogene |
| GPR87 | G protein-coupled receptor 87 |
| HIST1H2AL | histone cluster 1, H2al |
| HOXC5 | homeobox C5 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL22 | interleukin 22 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JRKL | JRK-like |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIF13B | kinesin family member 13B |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MEFV | Mediterranean fever |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NCALD | neurocalcin delta |
| NOL12 | nucleolar protein 12 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G15 | phospholipase A2, group XV |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RIN1 | Ras and Rab interactor 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SPATA2L | spermatogenesis associated 2-like |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TESC | tescalcin |
| THBS3 | thrombospondin 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM242 | transmembrane protein 242 |
| TOM1 | target of myb1 (chicken) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPYL2 | TSPY-like 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBG2 | tubulin, gamma 2 |
| UBXN6 | UBX domain protein 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH1 | vasohibin 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGF | VGF nerve growth factor inducible |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF282 | zinc finger protein 282 |
| ZNF324 | zinc finger protein 324 |
| ZNF552 | zinc finger protein 552 |
| ZNF639 | zinc finger protein 639 |
| ZNF787 | zinc finger protein 787 |
| ZNF862 | zinc finger protein 862 |
