| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the diclofenac-445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANGPTL2 | angiopoietin-like 2 |
| ANK1 | ankyrin 1, erythrocytic |
| AQP6 | aquaporin 6, kidney specific |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CAV3 | caveolin 3 |
| CEP162 | centrosomal protein 162kDa |
| CTSE | cathepsin E |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DRG2 | developmentally regulated GTP binding protein 2 |
| DXO | decapping exoribonuclease |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| E2F6 | E2F transcription factor 6 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| ELMO2 | engulfment and cell motility 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EVPL | envoplakin |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FOSL2 | FOS-like antigen 2 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GALR3 | galanin receptor 3 |
| GSK3A | glycogen synthase kinase 3 alpha |
| H2AFY2 | H2A histone family, member Y2 |
| HABP2 | hyaluronan binding protein 2 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INO80B | INO80 complex subunit B |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLHL25 | kelch-like family member 25 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LINC01558 | long intergenic non-protein coding RNA 1558 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LY6G6E | lymphocyte antigen 6 complex, locus G6E (pseudogene) |
| MIP | major intrinsic protein of lens fiber |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MST1 | macrophage stimulating 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NCS1 | neuronal calcium sensor 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NIPAL3 | NIPA-like domain containing 3 |
| NOTCH2 | notch 2 |
| NRXN1 | neurexin 1 |
| NXPH4 | neurexophilin 4 |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| PCDH11Y | protocadherin 11 Y-linked |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLA2G5 | phospholipase A2, group V |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PODNL1 | podocan-like 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRSS8 | protease, serine, 8 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAB5C | RAB5C, member RAS oncogene family |
| RARG | retinoic acid receptor, gamma |
| RC3H2 | ring finger and CCCH-type domains 2 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| SDPR | serum deprivation response |
| SH2D3A | SH2 domain containing 3A |
| SLA | Src-like-adaptor |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SNPH | syntaphilin |
| SP1 | Sp1 transcription factor |
| SPN | sialophorin |
| TGM3 | transglutaminase 3 |
| THBS3 | thrombospondin 3 |
| TLN2 | talin 2 |
| TMEM53 | transmembrane protein 53 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UBE3A | ubiquitin protein ligase E3A |
| UTRN | utrophin |
| VWA5A | von Willebrand factor A domain containing 5A |
| WDR1 | WD repeat domain 1 |
| WDR48 | WD repeat domain 48 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF460 | zinc finger protein 460 |
| ZNF507 | zinc finger protein 507 |
| ZNF771 | zinc finger protein 771 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATF7 | activating transcription factor 7 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BEST2 | bestrophin 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C19ORF57 | chromosome 19 open reading frame 57 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC91 | coiled-coil domain containing 91 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD70 | CD70 molecule |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEP170B | centrosomal protein 170B |
| CEPT1 | choline/ethanolamine phosphotransferase 1 |
| CETN1 | centrin, EF-hand protein, 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CRYAB | crystallin, alpha B |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYB5R3 | cytochrome b5 reductase 3 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DENND4C | DENN/MADD domain containing 4C |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM222B | family with sequence similarity 222, member B |
| FOXC1 | forkhead box C1 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLMN | glomulin, FKBP associated protein |
| GPR3 | G protein-coupled receptor 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HDAC5 | histone deacetylase 5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| KCNJ10 | potassium channel, inwardly rectifying subfamily J, member 10 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLHL28 | kelch-like family member 28 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LDHC | lactate dehydrogenase C |
| LGALS13 | lectin, galactoside-binding, soluble, 13 |
| LSR | lipolysis stimulated lipoprotein receptor |
| MELK | maternal embryonic leucine zipper kinase |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MMP8 | matrix metallopeptidase 8 |
| MRPL35 | mitochondrial ribosomal protein L35 |
| MT1M | metallothionein 1M |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLM | polymerase (DNA directed), mu |
| POU5F1B | POU class 5 homeobox 1B |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTX3 | pentraxin 3, long |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASL10A | RAS-like, family 10, member A |
| RNF208 | ring finger protein 208 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RSF1 | remodeling and spacing factor 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SPAG16 | sperm associated antigen 16 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SYT17 | synaptotagmin XVII |
| SYT2 | synaptotagmin II |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRIM5 | tripartite motif containing 5 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TYR | tyrosinase |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF408 | zinc finger protein 408 |
| ZNF432 | zinc finger protein 432 |
| ZNF696 | zinc finger protein 696 |
