| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the diclofenac-7215 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALD1 | caldesmon 1 |
| CAPN5 | calpain 5 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD200 | CD200 molecule |
| CES3 | carboxylesterase 3 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLCA1 | chloride channel accessory 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| DACH1 | dachshund family transcription factor 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DPYS | dihydropyrimidinase |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FLJ11292 | |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GMPR | guanosine monophosphate reductase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPR176 | G protein-coupled receptor 176 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase |
| HIST1H2BN | histone cluster 1, H2bn |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFT122 | intraflagellar transport 122 |
| ING2 | inhibitor of growth family, member 2 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| ITGA10 | integrin, alpha 10 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT19P2 | keratin 19 pseudogene 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPXN | leupaxin |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAOA | monoamine oxidase A |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MEF2C | myocyte enhancer factor 2C |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| NAAA | N-acylethanolamine acid amidase |
| NCOA2 | nuclear receptor coactivator 2 |
| NEB | nebulin |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OCA2 | oculocutaneous albinism II |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OTUD4 | OTU deubiquitinase 4 |
| PAPOLA | poly(A) polymerase alpha |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIP | prolactin-induced protein |
| PRMT2IP | PRMT2 interacting protein |
| PRSS16 | protease, serine, 16 (thymus) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RAD51 | RAD51 recombinase |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RGS12 | regulator of G-protein signaling 12 |
| RNF170 | ring finger protein 170 |
| RUNX1 | runt-related transcription factor 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SGSM3 | small G protein signaling modulator 3 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNPO | synaptopodin |
| TAOK2 | TAO kinase 2 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TUBA3C | tubulin, alpha 3c |
| USP34 | ubiquitin specific peptidase 34 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF358 | zinc finger protein 358 |
| ZNF770 | zinc finger protein 770 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ALPK1 | alpha-kinase 1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CBX4 | chromobox homolog 4 |
| CCNO | cyclin O |
| CD302 | CD302 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPQ | centromere protein Q |
| CEP85 | centrosomal protein 85kDa |
| CLDN15 | claudin 15 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DUSP8 | dual specificity phosphatase 8 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPHA2 | EPH receptor A2 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRAMD4 | GRAM domain containing 4 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GTPBP6 | GTP binding protein 6 (putative) |
| H2AFJ | H2A histone family, member J |
| KLHL26 | kelch-like family member 26 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINS | lines homolog (Drosophila) |
| LMNB1 | lamin B1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MED15 | mediator complex subunit 15 |
| MMP9 | matrix metallopeptidase 9 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NAV2 | neuron navigator 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NRSN2 | neurensin 2 |
| PDZD8 | PDZ domain containing 8 |
| PGP | phosphoglycolate phosphatase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLD3 | phospholipase D family, member 3 |
| POLH | polymerase (DNA directed), eta |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RBL1 | retinoblastoma-like 1 |
| REST | RE1-silencing transcription factor |
| RNF2 | ring finger protein 2 |
| RNF25 | ring finger protein 25 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIK1 | salt-inducible kinase 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPIDR | scaffolding protein involved in DNA repair |
| TBL3 | transducin (beta)-like 3 |
| TESK1 | testis-specific kinase 1 |
| TFB1M | transcription factor B1, mitochondrial |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLN1 | talin 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMC5 | transmembrane channel-like 5 |
| TMEM104 | transmembrane protein 104 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASH1 | vasohibin 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| WDR62 | WD repeat domain 62 |
| YBX2 | Y box binding protein 2 |
| ZNF219 | zinc finger protein 219 |
| ZNF468 | zinc finger protein 468 |
| ZNF552 | zinc finger protein 552 |
| ZNF573 | zinc finger protein 573 |
| ZNF668 | zinc finger protein 668 |
| ZNF7 | zinc finger protein 7 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF778 | zinc finger protein 778 |