| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the diclofenamide-3366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AVPR1A | arginine vasopressin receptor 1A |
| BARX2 | BARX homeobox 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BHMT | betaine--homocysteine S-methyltransferase |
| BMP10 | bone morphogenetic protein 10 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD22 | CD22 molecule |
| CDH8 | cadherin 8, type 2 |
| CFAP45 | cilia and flagella associated protein 45 |
| CLEC4M | C-type lectin domain family 4, member M |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCT | dopachrome tautomerase |
| DEFA4 | defensin, alpha 4, corticostatin |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNASE1 | deoxyribonuclease I |
| EFCAB6 | EF-hand calcium binding domain 6 |
| ELL | elongation factor RNA polymerase II |
| ERCC2 | excision repair cross-complementation group 2 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FGF4 | fibroblast growth factor 4 |
| FMO5 | flavin containing monooxygenase 5 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FST | follistatin |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSN | gelsolin |
| HHLA1 | HERV-H LTR-associating 1 |
| HOXD11 | homeobox D11 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGHD | immunoglobulin heavy constant delta |
| IL11 | interleukin 11 |
| IL17RC | interleukin 17 receptor C |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA0509 | uncharacterized LOC57242 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LOC51145 | uncharacterized LOC51145 |
| LTC4S | leukotriene C4 synthase |
| MDM4 | MDM4, p53 regulator |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MORN1 | MORN repeat containing 1 |
| MST1 | macrophage stimulating 1 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYT1 | myelin transcription factor 1 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NNAT | neuronatin |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NTF3 | neurotrophin 3 |
| NUP214 | nucleoporin 214kDa |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OMG | oligodendrocyte myelin glycoprotein |
| PARVA | parvin, alpha |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHF20L1 | PHD finger protein 20-like 1 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POU3F2 | POU class 3 homeobox 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PVRIG | poliovirus receptor related immunoglobulin domain containing |
| PYY | peptide YY |
| RAB6B | RAB6B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| REEP2 | receptor accessory protein 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RORC | RAR-related orphan receptor C |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SIRT5 | sirtuin 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNCAIP | synuclein, alpha interacting protein |
| SOAT2 | sterol O-acyltransferase 2 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYN3 | synapsin III |
| TBX5 | T-box 5 |
| TBX6 | T-box 6 |
| TGM4 | transglutaminase 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADM | adrenomedullin |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AXIN1 | axin 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C5 | complement component 5 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CALML5 | calmodulin-like 5 |
| CCDC186 | coiled-coil domain containing 186 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDK20 | cyclin-dependent kinase 20 |
| CENPO | centromere protein O |
| CORO7 | coronin 7 |
| CORT | cortistatin |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DENND4C | DENN/MADD domain containing 4C |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERCC4 | excision repair cross-complementation group 4 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT22 | intraflagellar transport 22 |
| IPP | intracisternal A particle-promoted polypeptide |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAGEA3 | melanoma antigen family A3 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBTD1 | mbt domain containing 1 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NME5 | NME/NM23 family member 5 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| ONECUT2 | one cut homeobox 2 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE12 | phosphodiesterase 12 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PODNL1 | podocan-like 1 |
| POLH | polymerase (DNA directed), eta |
| POLM | polymerase (DNA directed), mu |
| POM121 | POM121 transmembrane nucleoporin |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SECTM1 | secreted and transmembrane 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TDRD1 | tudor domain containing 1 |
| TEP1 | telomerase-associated protein 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TIPRL | TOR signaling pathway regulator |
| TPCN1 | two pore segment channel 1 |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| VEGFC | vascular endothelial growth factor C |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF160 | zinc finger protein 160 |
| ZNF304 | zinc finger protein 304 |
| ZNF430 | zinc finger protein 430 |
| ZNF551 | zinc finger protein 551 |
| ZNF611 | zinc finger protein 611 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
| ZNF721 | zinc finger protein 721 |
