dicloxacillin-2445 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dicloxacillin-2445 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAM19 ADAM metallopeptidase domain 19
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AIRE autoimmune regulator
ANKRD7 ankyrin repeat domain 7
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOC4 apolipoprotein C-IV
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
B9D1 B9 protein domain 1
BCL2L1 BCL2-like 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C11ORF16 chromosome 11 open reading frame 16
C7 complement component 7
CALD1 caldesmon 1
CCL13 chemokine (C-C motif) ligand 13
CD36 CD36 molecule (thrombospondin receptor)
CD6 CD6 molecule
CDC14B cell division cycle 14B
CELA2A chymotrypsin-like elastase family, member 2A
CFAP45 cilia and flagella associated protein 45
CFAP74 cilia and flagella associated protein 74
CHGA chromogranin A
CNGB3 cyclic nucleotide gated channel beta 3
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COX11 COX11 cytochrome c oxidase copper chaperone
CSF1 colony stimulating factor 1 (macrophage)
CTNND1 catenin (cadherin-associated protein), delta 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DLX2 distal-less homeobox 2
DTNB dystrobrevin, beta
DZIP3 DAZ interacting zinc finger protein 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAM65B family with sequence similarity 65, member B
FERMT1 fermitin family member 1
FGF6 fibroblast growth factor 6
FXYD2 FXYD domain containing ion transport regulator 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAL galanin/GMAP prepropeptide
GFER growth factor, augmenter of liver regeneration
GPATCH4 G patch domain containing 4
GRIA1 glutamate receptor, ionotropic, AMPA 1
GSK3A glycogen synthase kinase 3 alpha
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AL histone cluster 1, H2al
HNF4A hepatocyte nuclear factor 4, alpha
HR hair growth associated
IFNB1 interferon, beta 1, fibroblast
IGFBP5 insulin-like growth factor binding protein 5
IL33R interleukin 33 receptor
KLHL1 kelch-like family member 1
LENEP lens epithelial protein
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAP6D1 MAP6 domain containing 1
MC3R melanocortin 3 receptor
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MORC1 MORC family CW-type zinc finger 1
MSI1 musashi RNA-binding protein 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO6 myosin VI
NAG18 NAG18 mRNA
NECAB2 N-terminal EF-hand calcium binding protein 2
NF2 neurofibromin 2 (merlin)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPPA natriuretic peptide A
PAX2 paired box 2
PDE4C phosphodiesterase 4C, cAMP-specific
PDLIM7 PDZ and LIM domain 7 (enigma)
PIGR polymeric immunoglobulin receptor
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCH1 phospholipase C, eta 1
POU5F1P4 POU class 5 homeobox 1 pseudogene 4
PSG4 pregnancy specific beta-1-glycoprotein 4
RHOD ras homolog family member D
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SAA3P serum amyloid A3 pseudogene
SCUBE3 signal peptide, CUB domain, EGF-like 3
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIL1 SIL1 nucleotide exchange factor
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT13 synaptotagmin XIII
TAS2R1 taste receptor, type 2, member 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX2 T-box 2
TEF thyrotrophic embryonic factor
TFDP3 transcription factor Dp family, member 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM176B transmembrane protein 176B
TMPRSS6 transmembrane protease, serine 6
TRIM3 tripartite motif containing 3
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
ULBP1 UL16 binding protein 1
VCX2 variable charge, X-linked 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGAP12 Rho GTPase activating protein 12
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
C11ORF49 chromosome 11 open reading frame 49
C1ORF56 chromosome 1 open reading frame 56
C22ORF29 chromosome 22 open reading frame 29
CCDC69 coiled-coil domain containing 69
CD320 CD320 molecule
CD37 CD37 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD69 CD69 molecule
CHMP7 charged multivesicular body protein 7
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRIP1 cysteine-rich protein 1 (intestinal)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTNNBL1 catenin, beta like 1
CYTIP cytohesin 1 interacting protein
DAAM1 dishevelled associated activator of morphogenesis 1
DENND4C DENN/MADD domain containing 4C
DOLK dolichol kinase
EMILIN2 elastin microfibril interfacer 2
ENO2 enolase 2 (gamma, neuronal)
ERO1LB ERO1-like beta (S. cerevisiae)
FAM102A family with sequence similarity 102, member A
FAM127B family with sequence similarity 127, member B
FAM63B family with sequence similarity 63, member B
FGGY FGGY carbohydrate kinase domain containing
FKBP9 FK506 binding protein 9, 63 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALK1 galactokinase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GIN1 gypsy retrotransposon integrase 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH3 G patch domain containing 3
GPNMB glycoprotein (transmembrane) nmb
GYS1 glycogen synthase 1 (muscle)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOPX HOP homeobox
HPSE heparanase
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFT81 intraflagellar transport 81
ITGAV integrin, alpha V
KIAA0232 KIAA0232
KIAA0753 KIAA0753
LIG4 ligase IV, DNA, ATP-dependent
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
METTL1 methyltransferase like 1
MOCS3 molybdenum cofactor synthesis 3
MTERF1 mitochondrial transcription termination factor 1
NFE2L3 nuclear factor, erythroid 2-like 3
PANX1 pannexin 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDZD7 PDZ domain containing 7
PECR peroxisomal trans-2-enoyl-CoA reductase
PHACTR1 phosphatase and actin regulator 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PORCN porcupine homolog (Drosophila)
PPARG peroxisome proliferator-activated receptor gamma
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
PRKCZ protein kinase C, zeta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SERINC5 serine incorporator 5
SLC25A40 solute carrier family 25, member 40
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLITRK5 SLIT and NTRK-like family, member 5
SPAG4 sperm associated antigen 4
SPATA20 spermatogenesis associated 20
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SYNJ2BP synaptojanin 2 binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBCCD1 TBCC domain containing 1
TESK2 testis-specific kinase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM242 transmembrane protein 242
TMEM45A transmembrane protein 45A
TRIM36 tripartite motif containing 36
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
TTPAL tocopherol (alpha) transfer protein-like
WRB tryptophan rich basic protein
ZNF273 zinc finger protein 273
ZNF408 zinc finger protein 408
ZNF468 zinc finger protein 468
ZNF493 zinc finger protein 493
ZNF536 zinc finger protein 536
ZNF76 zinc finger protein 76
ZNF83 zinc finger protein 83