dicloxacillin-5012 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dicloxacillin-5012 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKR1C1 aldo-keto reductase family 1, member C1
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARHGAP1 Rho GTPase activating protein 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BMP8B bone morphogenetic protein 8b
CALU calumenin
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFAP69 cilia and flagella associated protein 69
CLDN1 claudin 1
CNTN1 contactin 1
CPA4 carboxypeptidase A4
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CYTH1 cytohesin 1
DAZAP2 DAZ associated protein 2
DCAF15 DDB1 and CUL4 associated factor 15
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEDD death effector domain containing
DHRS2 dehydrogenase/reductase (SDR family) member 2
DICER1 dicer 1, ribonuclease type III
EHD1 EH-domain containing 1
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EMC1 ER membrane protein complex subunit 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FGF22 fibroblast growth factor 22
GNAS GNAS complex locus
GPR143 G protein-coupled receptor 143
GSPT1 G1 to S phase transition 1
GTF2I general transcription factor IIi
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIPK3 homeodomain interacting protein kinase 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
ING1 inhibitor of growth family, member 1
KITLG KIT ligand
KLHL25 kelch-like family member 25
LAMP1 lysosomal-associated membrane protein 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMAN1 lectin, mannose-binding, 1
LPIN1 lipin 1
MAPK13 mitogen-activated protein kinase 13
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED20 mediator complex subunit 20
METTL16 methyltransferase like 16
MTMR1 myotubularin related protein 1
NDRG2 NDRG family member 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR2F1 nuclear receptor subfamily 2, group F, member 1
PCNX pecanex homolog (Drosophila)
PHTF2 putative homeodomain transcription factor 2
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLD2 phospholipase D2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKCI protein kinase C, iota
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVR poliovirus receptor
RAB6A RAB6A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RARG retinoic acid receptor, gamma
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
S100A8 S100 calcium binding protein A8
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SIRT5 sirtuin 5
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMAD3 SMAD family member 3
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNX13 sorting nexin 13
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STK16 serine/threonine kinase 16
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBC1D5 TBC1 domain family, member 5
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TFF2 trefoil factor 2
THBS1 thrombospondin 1
TLR5 toll-like receptor 5
TMED2 transmembrane emp24 domain trafficking protein 2
TYRP1 tyrosinase-related protein 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WDTC1 WD and tetratricopeptide repeats 1
WSB1 WD repeat and SOCS box containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF76 zinc finger protein 76
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACAD10 acyl-CoA dehydrogenase family, member 10
ADTRP androgen-dependent TFPI-regulating protein
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
B9D2 B9 protein domain 2
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
C8ORF60 chromosome 8 open reading frame 60
CBX4 chromobox homolog 4
CDHR2 cadherin-related family member 2
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CGREF1 cell growth regulator with EF-hand domain 1
CIDEB cell death-inducing DFFA-like effector b
CNGB3 cyclic nucleotide gated channel beta 3
CPEB3 cytoplasmic polyadenylation element binding protein 3
CUL9 cullin 9
DCP1A decapping mRNA 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM1 dynamin 1
DUSP8 dual specificity phosphatase 8
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EN2 engrailed homeobox 2
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FBXL15 F-box and leucine-rich repeat protein 15
FGL1 fibrinogen-like 1
FZD4 frizzled class receptor 4
GADD45G growth arrest and DNA-damage-inducible, gamma
GCHFR GTP cyclohydrolase I feedback regulator
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR1 G protein-coupled receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDAC11 histone deacetylase 11
IL15RA interleukin 15 receptor, alpha
IL22 interleukin 22
INO80D INO80 complex subunit D
ITGA10 integrin, alpha 10
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
LHX6 LIM homeobox 6
LRP3 low density lipoprotein receptor-related protein 3
LRRC20 leucine rich repeat containing 20
LRRC61 leucine rich repeat containing 61
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MALL mal, T-cell differentiation protein-like
MFSD11 major facilitator superfamily domain containing 11
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MSI1 musashi RNA-binding protein 1
MYOZ3 myozenin 3
N4BP3 NEDD4 binding protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NPR3 natriuretic peptide receptor 3
NT5DC3 5'-nucleotidase domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PCDHA9 protocadherin alpha 9
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POPDC3 popeye domain containing 3
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRPH peripherin
PRSS16 protease, serine, 16 (thymus)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB3A RAB3A, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFPL1S RFPL1 antisense RNA 1
RGS2 regulator of G-protein signaling 2
RNF122 ring finger protein 122
S100A9 S100 calcium binding protein A9
SAMHD1 SAM domain and HD domain 1
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SKI SKI proto-oncogene
SLC12A9 solute carrier family 12, member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA2L spermatogenesis associated 2-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYCP2 synaptonemal complex protein 2
TH tyrosine hydroxylase
TM7SF3 transmembrane 7 superfamily member 3
TMEM45A transmembrane protein 45A
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA4B tubulin, alpha 4b
UPK3B uroplakin 3B
USP19 ubiquitin specific peptidase 19
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR25 WD repeat domain 25
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862