dicoumarol-2561 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the dicoumarol-2561 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM7 ADAM metallopeptidase domain 7
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRB3 adrenoceptor beta 3
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
AMACR alpha-methylacyl-CoA racemase
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD53 ankyrin repeat domain 53
APOA1 apolipoprotein A-I
APOC1 apolipoprotein C-I
BCAM basal cell adhesion molecule (Lutheran blood group)
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
C7ORF26 chromosome 7 open reading frame 26
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALD1 caldesmon 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC170 coiled-coil domain containing 170
CCL27 chemokine (C-C motif) ligand 27
CCNK cyclin K
CD52 CD52 molecule
CD6 CD6 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC10A C-type lectin domain family 10, member A
COL14A1 collagen, type XIV, alpha 1
COL8A1 collagen, type VIII, alpha 1
DAPK3 death-associated protein kinase 3
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DUSP21 dual specificity phosphatase 21
EBF2 early B-cell factor 2
EFS embryonal Fyn-associated substrate
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF22 fibroblast growth factor 22
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FRAS1 Fraser extracellular matrix complex subunit 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLYAT glycine-N-acyltransferase
GRIK2 glutamate receptor, ionotropic, kainate 2
HOXD3 homeobox D3
HPR haptoglobin-related protein
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
IGFBP5 insulin-like growth factor binding protein 5
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0895 KIAA0895
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLF6 Kruppel-like factor 6
LHX2 LIM homeobox 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEG3 maternally expressed 3 (non-protein coding)
MIA2 melanoma inhibitory activity 2
MIR22HG MIR22 host gene
MPPE1 metallophosphoesterase 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NRG2 neuregulin 2
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDE4D phosphodiesterase 4D, cAMP-specific
PLA2G3 phospholipase A2, group III
PMP2 peripheral myelin protein 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTPRB protein tyrosine phosphatase, receptor type, B
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
SCAND2P SCAN domain containing 2 pseudogene
SCARB2 scavenger receptor class B, member 2
SEMG2 semenogelin II
SERHL2 serine hydrolase-like 2
SIX3 SIX homeobox 3
SLC16A6 solute carrier family 16, member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SYT5 synaptotagmin V
TAPT1 transmembrane anterior posterior transformation 1
TBX6 T-box 6
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM180 transmembrane protein 180
TMEM51 transmembrane protein 51
TRAPPC9 trafficking protein particle complex 9
TRO trophinin
TSKU tsukushi, small leucine rich proteoglycan
ZNF155 zinc finger protein 155
ZNF385D zinc finger protein 385D
ZNF440 zinc finger protein 440
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ATG9A autophagy related 9A
BAG4 BCL2-associated athanogene 4
BBC3 BCL2 binding component 3
C12ORF49 chromosome 12 open reading frame 49
C17ORF70 chromosome 17 open reading frame 70
C1QTNF3 C1q and tumor necrosis factor related protein 3
C8ORF44 chromosome 8 open reading frame 44
CCDC69 coiled-coil domain containing 69
CD2AP CD2-associated protein
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP7 charged multivesicular body protein 7
CLCF1 cardiotrophin-like cytokine factor 1
CLEC2B C-type lectin domain family 2, member B
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTPS2 CTP synthase 2
CUL9 cullin 9
DKK2 dickkopf WNT signaling pathway inhibitor 2
ELP6 elongator acetyltransferase complex subunit 6
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC3 excision repair cross-complementation group 3
ERI3 ERI1 exoribonuclease family member 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM53C family with sequence similarity 53, member C
FANCF Fanconi anemia, complementation group F
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GDAP2 ganglioside induced differentiation associated protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
HCAR3 hydroxycarboxylic acid receptor 3
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
IFT46 intraflagellar transport 46
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL18 interleukin 18
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA1024 KIAA1024
KIF1B kinesin family member 1B
LEMD3 LEM domain containing 3
LIMA1 LIM domain and actin binding 1
LIN7A lin-7 homolog A (C. elegans)
LRP10 low density lipoprotein receptor-related protein 10
LRP5 low density lipoprotein receptor-related protein 5
MAN2C1 mannosidase, alpha, class 2C, member 1
MNS1 meiosis-specific nuclear structural 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NOD1 nucleotide-binding oligomerization domain containing 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NUBPL nucleotide binding protein-like
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PES1 pescadillo ribosomal biogenesis factor 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHYH phytanoyl-CoA 2-hydroxylase
PLS1 plastin 1
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POMZP3 POM121 and ZP3 fusion
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRR14L proline rich 14-like
PRR4 proline rich 4 (lacrimal)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
RC3H2 ring finger and CCCH-type domains 2
RFXAP regulatory factor X-associated protein
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RPL39L ribosomal protein L39-like
SCML1 sex comb on midleg-like 1 (Drosophila)
SERINC5 serine incorporator 5
SF3B2 splicing factor 3b, subunit 2, 145kDa
SLFN12 schlafen family member 12
SOAT1 sterol O-acyltransferase 1
TBK1 TANK-binding kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGDS TDP-glucose 4,6-dehydratase
TMEM115 transmembrane protein 115
TMEM242 transmembrane protein 242
TMEM246 transmembrane protein 246
TOLLIP toll interacting protein
TRIB1 tribbles pseudokinase 1
UNC13B unc-13 homolog B (C. elegans)
XYLT2 xylosyltransferase II
ZBTB10 zinc finger and BTB domain containing 10
ZFP30 ZFP30 zinc finger protein
ZHX2 zinc fingers and homeoboxes 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF232 zinc finger protein 232
ZNF331 zinc finger protein 331
ZNF506 zinc finger protein 506
ZNF571 zinc finger protein 571