dicoumarol-3423 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the dicoumarol-3423 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABR active BCR-related
ADAP1 ArfGAP with dual PH domains 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARTN artemin
ASPH aspartate beta-hydroxylase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BIRC7 baculoviral IAP repeat containing 7
BPGM 2,3-bisphosphoglycerate mutase
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF21 chromosome 11 open reading frame 21
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCNO cyclin O
CD22 CD22 molecule
CD44 CD44 molecule (Indian blood group)
CDC14B cell division cycle 14B
CDK19 cyclin-dependent kinase 19
CENPO centromere protein O
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL7A1 collagen, type VII, alpha 1
COMT catechol-O-methyltransferase
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DMPK dystrophia myotonica-protein kinase
DOCK6 dedicator of cytokinesis 6
DPYSL4 dihydropyrimidinase-like 4
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP4 dual specificity phosphatase 4
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPOR erythropoietin receptor
ESR2 estrogen receptor 2 (ER beta)
FAXDC2 fatty acid hydroxylase domain containing 2
FHL1 four and a half LIM domains 1
FKBP5 FK506 binding protein 5
FSCN1 fascin actin-bundling protein 1
GAMT guanidinoacetate N-methyltransferase
HBEGF heparin-binding EGF-like growth factor
HDAC7 histone deacetylase 7
IDI2-AS1 IDI2 antisense RNA 1
IGFBP5 insulin-like growth factor binding protein 5
IL22 interleukin 22
IQCE IQ motif containing E
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MASP2 mannan-binding lectin serine peptidase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MST1L macrophage stimulating 1-like
MUC1 mucin 1, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NMT1 N-myristoyltransferase 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPTN optineurin
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA6 protocadherin alpha 6
PCDHB13 protocadherin beta 13
PICALM phosphatidylinositol binding clathrin assembly protein
PITX1 paired-like homeodomain 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRDM2 PR domain containing 2, with ZNF domain
PTCRA pre T-cell antigen receptor alpha
PTRF polymerase I and transcript release factor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51 RAD51 recombinase
RARA retinoic acid receptor, alpha
RASAL2 RAS protein activator like 2
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RNF6 ring finger protein (C3H2C3 type) 6
RPL10L ribosomal protein L10-like
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCAF4 SR-related CTD-associated factor 4
SCML2 sex comb on midleg-like 2 (Drosophila)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIN3B SIN3 transcription regulator family member B
SLC35E2 solute carrier family 35, member E2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTBN1 spectrin, beta, non-erythrocytic 1
STX5 syntaxin 5
TAZ tafazzin
TCF3 transcription factor 3
TNS1 tensin 1
ZBTB6 zinc finger and BTB domain containing 6
ZIC3 Zic family member 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF253 zinc finger protein 253
ZNF3 zinc finger protein 3
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACVR2B activin A receptor, type IIB
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ATP13A2 ATPase type 13A2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
BBS10 Bardet-Biedl syndrome 10
BCORL1 BCL6 corepressor-like 1
BFSP1 beaded filament structural protein 1, filensin
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CAPN1 calpain 1, (mu/I) large subunit
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPT centromere protein T
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIC capicua transcriptional repressor
CIT citron rho-interacting serine/threonine kinase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA4 EPH receptor A4
GMEB1 glucocorticoid modulatory element binding protein 1
GSTT1 glutathione S-transferase theta 1
GTPBP2 GTP binding protein 2
HIRA histone cell cycle regulator
HIST1H2BC histone cluster 1, H2bc
HTT huntingtin
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF6 interferon regulatory factor 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KIF18A kinesin family member 18A
LINC00339 long intergenic non-protein coding RNA 339
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC16A leucine rich repeat containing 16A
LRRC61 leucine rich repeat containing 61
LYPLA2P1 lysophospholipase II pseudogene 1
LZTR1 leucine-zipper-like transcription regulator 1
MANBA mannosidase, beta A, lysosomal
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK12 mitogen-activated protein kinase 12
MCOLN3 mucolipin 3
MFSD11 major facilitator superfamily domain containing 11
MGC12488
NBEAL2 neurobeachin-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NT5DC3 5'-nucleotidase domain containing 3
OTUD3 OTU deubiquitinase 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP16 poly (ADP-ribose) polymerase family, member 16
PC pyruvate carboxylase
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLA2G3 phospholipase A2, group III
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPGR retinitis pigmentosa GTPase regulator
SCAMP5 secretory carrier membrane protein 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1B SET domain containing 1B
SIRT6 sirtuin 6
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNHG3 small nucleolar RNA host gene 3
SOWAHC sosondowah ankyrin repeat domain family member C
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUSD6 sushi domain containing 6
TEAD3 TEA domain family member 3
TMEM104 transmembrane protein 104
TMEM132A transmembrane protein 132A
TMEM159 transmembrane protein 159
TMEM180 transmembrane protein 180
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNIP1 TNFAIP3 interacting protein 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAIP TRAF interacting protein
TRIM66 tripartite motif containing 66
TTBK2 tau tubulin kinase 2
WDR4 WD repeat domain 4
XK X-linked Kx blood group
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF141 zinc finger protein 141
ZNF324 zinc finger protein 324
ZNF652 zinc finger protein 652
ZNF696 zinc finger protein 696
ZNF721 zinc finger protein 721
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31