dicoumarol-3766 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the dicoumarol-3766 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADCK2 aarF domain containing kinase 2
ADGRG1 adhesion G protein-coupled receptor G1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALPP alkaline phosphatase, placental
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP9B ATPase, class II, type 9B
BBC3 BCL2 binding component 3
C1ORF61 chromosome 1 open reading frame 61
C21ORF2 chromosome 21 open reading frame 2
C7ORF69 chromosome 7 open reading frame 69
CD1E CD1e molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CHAT choline O-acetyltransferase
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLEC4E C-type lectin domain family 4, member E
COL4A4 collagen, type IV, alpha 4
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPF1 D4, zinc and double PHD fingers family 1
EFNB3 ephrin-B3
EMID1 EMI domain containing 1
ERN1 endoplasmic reticulum to nucleus signaling 1
FGB fibrinogen beta chain
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GBP1 guanylate binding protein 1, interferon-inducible
GIMAP6 GTPase, IMAP family member 6
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GRM1 glutamate receptor, metabotropic 1
HBB hemoglobin, beta
HEMK1 HemK methyltransferase family member 1
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
IFNA2 interferon, alpha 2
ING4 inhibitor of growth family, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA0319L KIAA0319-like
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF13 Kruppel-like factor 13
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
LMO1 LIM domain only 1 (rhombotin 1)
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAPK14 mitogen-activated protein kinase 14
MEGF8 multiple EGF-like-domains 8
MMP11 matrix metallopeptidase 11
MUC6 mucin 6, oligomeric mucus/gel-forming
MYBPC3 myosin binding protein C, cardiac
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
MYOZ3 myozenin 3
NDRG2 NDRG family member 2
NPR1 natriuretic peptide receptor 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PARVA parvin, alpha
PCDHB13 protocadherin beta 13
PDC phosducin
PNMAL1 paraneoplastic Ma antigen family-like 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRSS50 protease, serine, 50
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RAMP2 receptor (G protein-coupled) activity modifying protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RS1 retinoschisin 1
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
SCLY selenocysteine lyase
SKIL SKI-like proto-oncogene
SLAMF7 SLAM family member 7
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLIT3 slit homolog 3 (Drosophila)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOS2 son of sevenless homolog 2 (Drosophila)
SPRR1A small proline-rich protein 1A
STAT4 signal transducer and activator of transcription 4
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TGM4 transglutaminase 4
THAP3 THAP domain containing, apoptosis associated protein 3
THY1 Thy-1 cell surface antigen
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM3 tripartite motif containing 3
UBA7 ubiquitin-like modifier activating enzyme 7
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VCX2 variable charge, X-linked 2
ZFP64 ZFP64 zinc finger protein
ZNF440 zinc finger protein 440
ZNF471 zinc finger protein 471

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACSS3 acyl-CoA synthetase short-chain family member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
AFAP1 actin filament associated protein 1
ANXA2P1 annexin A2 pseudogene 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BIRC3 baculoviral IAP repeat containing 3
C17ORF53 chromosome 17 open reading frame 53
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBX8 chromobox homolog 8
CCDC88C coiled-coil domain containing 88C
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CXCL2 chemokine (C-X-C motif) ligand 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EDN1 endothelin 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL7 F-box and leucine-rich repeat protein 7
GK3P glycerol kinase 3 pseudogene
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AJ histone cluster 1, H2aj
HMGB3P1 high mobility group box 3 pseudogene 1
HOXA7 homeobox A7
IL22 interleukin 22
INO80D INO80 complex subunit D
ITPKA inositol-trisphosphate 3-kinase A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCTD20 potassium channel tetramerization domain containing 20
KDM7A lysine (K)-specific demethylase 7A
LINC00472 long intergenic non-protein coding RNA 472
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPAR3 lysophosphatidic acid receptor 3
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPLA2P1 lysophospholipase II pseudogene 1
MFSD11 major facilitator superfamily domain containing 11
MXRA8 matrix-remodelling associated 8
NEK11 NIMA-related kinase 11
NME5 NME/NM23 family member 5
NOD1 nucleotide-binding oligomerization domain containing 1
NOL12 nucleolar protein 12
NUP62CL nucleoporin 62kDa C-terminal like
NYNRIN NYN domain and retroviral integrase containing
OSGIN1 oxidative stress induced growth inhibitor 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA2G15 phospholipase A2, group XV
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLXNB3 plexin B3
PMCH pro-melanin-concentrating hormone
POLL polymerase (DNA directed), lambda
PTPRU protein tyrosine phosphatase, receptor type, U
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S1PR1 sphingosine-1-phosphate receptor 1
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SOX12 SRY (sex determining region Y)-box 12
SPATA7 spermatogenesis associated 7
STX1A syntaxin 1A (brain)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TMEM159 transmembrane protein 159
TNRC6B trinucleotide repeat containing 6B
TNS2 tensin 2
TRAC T cell receptor alpha constant
TRAIP TRAF interacting protein
UNC119 unc-119 homolog (C. elegans)
VGLL3 vestigial-like family member 3
VLDLR very low density lipoprotein receptor
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP30 ZFP30 zinc finger protein
ZNF10 zinc finger protein 10
ZNF286A zinc finger protein 286A
ZNF408 zinc finger protein 408
ZNF862 zinc finger protein 862