dicoumarol-3941 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dicoumarol-3941 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADORA3 adenosine A3 receptor
AFF1 AF4/FMR2 family, member 1
ARHGAP1 Rho GTPase activating protein 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARL4D ADP-ribosylation factor-like 4D
ATP11A ATPase, class VI, type 11A
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BTN3A1 butyrophilin, subfamily 3, member A1
C11ORF16 chromosome 11 open reading frame 16
C1ORF54 chromosome 1 open reading frame 54
C1ORF95 chromosome 1 open reading frame 95
CA9 carbonic anhydrase IX
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCR4 chemokine (C-C motif) receptor 4
CD5 CD5 molecule
CD6 CD6 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CEP112 centrosomal protein 112kDa
CLDN18 claudin 18
CNTNAP3B contactin associated protein-like 3B
CPA3 carboxypeptidase A3 (mast cell)
CPQ carboxypeptidase Q
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTSZ cathepsin Z
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DHRS12 dehydrogenase/reductase (SDR family) member 12
DLX2 distal-less homeobox 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDNRA endothelin receptor type A
ELOVL2 ELOVL fatty acid elongase 2
ERC1 ELKS/RAB6-interacting/CAST family member 1
FLJ11292
GJD2 gap junction protein, delta 2, 36kDa
GPR21 G protein-coupled receptor 21
HERC2P3 hect domain and RLD 2 pseudogene 3
HIST1H2AB histone cluster 1, H2ab
HLF hepatic leukemia factor
ICOSLG inducible T-cell co-stimulator ligand
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL36G interleukin 36, gamma
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNIP1 Kv channel interacting protein 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF25 kinesin family member 25
KRT1 keratin 1, type II
KRT9 keratin 9, type I
LECT1 leukocyte cell derived chemotaxin 1
LHX3 LIM homeobox 3
LIMCH1 LIM and calponin homology domains 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEA5 melanoma antigen family A5
MAGEA6 melanoma antigen family A6
MEG3 maternally expressed 3 (non-protein coding)
MLN motilin
MUC8 mucin 8
MYBPC3 myosin binding protein C, cardiac
MYCNOS MYCN opposite strand
NCOR2 nuclear receptor corepressor 2
NCR3 natural cytotoxicity triggering receptor 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NRP1 neuropilin 1
NUDC nudC nuclear distribution protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAM peptidylglycine alpha-amidating monooxygenase
PAMR1 peptidase domain containing associated with muscle regeneration 1
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POLL polymerase (DNA directed), lambda
PON3 paraoxonase 3
POU3F4 POU class 3 homeobox 4
PQLC2 PQ loop repeat containing 2
PROL1 proline rich, lacrimal 1
PSAT1 phosphoserine aminotransferase 1
RBP4 retinol binding protein 4, plasma
REEP2 receptor accessory protein 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SIGLEC7 sialic acid binding Ig-like lectin 7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNCG synuclein, gamma (breast cancer-specific protein 1)
TAS2R4 taste receptor, type 2, member 4
TIMP3 TIMP metallopeptidase inhibitor 3
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
UGT8 UDP glycosyltransferase 8
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAP2 ArfGAP with dual PH domains 2
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
AHSP alpha hemoglobin stabilizing protein
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AUP1 ancient ubiquitous protein 1
BMP10 bone morphogenetic protein 10
C11ORF80 chromosome 11 open reading frame 80
C1QB complement component 1, q subcomponent, B chain
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARTPT CART prepropeptide
CCP110 centriolar coiled coil protein 110kDa
CD83 CD83 molecule
CDON cell adhesion associated, oncogene regulated
CHKB choline kinase beta
CLDN11 claudin 11
CORT cortistatin
DLL3 delta-like 3 (Drosophila)
DNM1 dynamin 1
DOC2A double C2-like domains, alpha
EPPK1 epiplakin 1
ETNK2 ethanolamine kinase 2
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FOXN2 forkhead box N2
FSTL1 follistatin-like 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR1 G protein-coupled receptor 1
GPR143 G protein-coupled receptor 143
GPR3 G protein-coupled receptor 3
GPRC5D G protein-coupled receptor, class C, group 5, member D
GREB1L growth regulation by estrogen in breast cancer-like
GSTTP1 glutathione S-transferase theta pseudogene 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIRA histone cell cycle regulator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC5 homeobox C5
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LMTK2 lemur tyrosine kinase 2
LOC100286895 cell division cycle 27 homolog pseudogene
LOC729164 hCG1732469
MAPK7 mitogen-activated protein kinase 7
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MX2 MX dynamin-like GTPase 2
MYLK myosin light chain kinase
NAT6 N-acetyltransferase 6 (GCN5-related)
NPY neuropeptide Y
NR2F6 nuclear receptor subfamily 2, group F, member 6
OSGIN1 oxidative stress induced growth inhibitor 1
PARD6A par-6 family cell polarity regulator alpha
PAX9 paired box 9
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIPOX pipecolic acid oxidase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PSCA prostate stem cell antigen
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB3A RAB3A, member RAS oncogene family
RAB40AL RAB40A, member RAS oncogene family-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF208 ring finger protein 208
RNF39 ring finger protein 39
SDC3 syndecan 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC12A8 solute carrier family 12, member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SOAT2 sterol O-acyltransferase 2
SPTBN2 spectrin, beta, non-erythrocytic 2
SSBP3 single stranded DNA binding protein 3
ST5 suppression of tumorigenicity 5
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLR2 toll-like receptor 2
TM4SF5 transmembrane 4 L six family member 5
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TSC22D4 TSC22 domain family, member 4
TTLL1 tubulin tyrosine ligase-like family member 1
UNC93B1 unc-93 homolog B1 (C. elegans)
UPP1 uridine phosphorylase 1
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
WLS wntless Wnt ligand secretion mediator
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZIC3 Zic family member 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862
ZXDB zinc finger, X-linked, duplicated B