dicycloverine-1902 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the dicycloverine-1902 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF2 activating transcription factor 2
ATP13A3 ATPase type 13A3
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BLZF1 basic leucine zipper nuclear factor 1
BMP2K BMP2 inducible kinase
CCDC88A coiled-coil domain containing 88A
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD70 CD70 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHD9 chromodomain helicase DNA binding protein 9
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CRCP CGRP receptor component
CTH cystathionine gamma-lyase
CXCL3 chemokine (C-X-C motif) ligand 3
DEGS1 delta(4)-desaturase, sphingolipid 1
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLK2 delta-like 2 homolog (Drosophila)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUS2 dihydrouridine synthase 2
EFNA1 ephrin-A1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGR1 early growth response 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EI24 etoposide induced 2.4
EID1 EP300 interacting inhibitor of differentiation 1
FDX1 ferredoxin 1
FSCN1 fascin actin-bundling protein 1
GLS glutaminase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AG histone cluster 1, H2ag
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
ICAM1 intercellular adhesion molecule 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFBP5 insulin-like growth factor binding protein 5
ING4 inhibitor of growth family, member 4
INHBA inhibin, beta A
KDM5A lysine (K)-specific demethylase 5A
KIAA1549L KIAA1549-like
KLF5 Kruppel-like factor 5 (intestinal)
KLHL21 kelch-like family member 21
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPTN kaptin (actin binding protein)
KRIT1 KRIT1, ankyrin repeat containing
KTN1 kinectin 1 (kinesin receptor)
LIN7C lin-7 homolog C (C. elegans)
LOC647070 uncharacterized LOC647070
LRP12 low density lipoprotein receptor-related protein 12
LRRC61 leucine rich repeat containing 61
MBD3 methyl-CpG binding domain protein 3
MCFD2 multiple coagulation factor deficiency 2
MCTP2 multiple C2 domains, transmembrane 2
MECP2 methyl CpG binding protein 2
MYL10 myosin, light chain 10, regulatory
OASL 2'-5'-oligoadenylate synthetase-like
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLSCR1 phospholipid scramblase 1
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPRF protein tyrosine phosphatase, receptor type, F
RHOQ ras homolog family member Q
RPL7 ribosomal protein L7
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
SAT1 spermidine/spermine N1-acetyltransferase 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEC23B Sec23 homolog B (S. cerevisiae)
SEZ6L seizure related 6 homolog (mouse)-like
SIN3B SIN3 transcription regulator family member B
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC5 structural maintenance of chromosomes 5
SMG7 SMG7 nonsense mediated mRNA decay factor
SMIM8 small integral membrane protein 8
SOS1 son of sevenless homolog 1 (Drosophila)
SP3 Sp3 transcription factor
ST20 suppressor of tumorigenicity 20
STAG2 stromal antigen 2
STXBP3 syntaxin binding protein 3
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TMED7 transmembrane emp24 protein transport domain containing 7
TPT1 tumor protein, translationally-controlled 1
TSC22D2 TSC22 domain family, member 2
VEZF1 vascular endothelial zinc finger 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR82 WD repeat domain 82
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YIPF4 Yip1 domain family, member 4
YIPF6 Yip1 domain family, member 6
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBTB39 zinc finger and BTB domain containing 39
ZMAT3 zinc finger, matrin-type 3
ZNF652 zinc finger protein 652
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASAP1-IT1 ASAP1 intronic transcript 1
BARD1 BRCA1 associated RING domain 1
BRIX1 BRX1, biogenesis of ribosomes
C16ORF62 chromosome 16 open reading frame 62
C19ORF24 chromosome 19 open reading frame 24
C6ORF47 chromosome 6 open reading frame 47
CBR1 carbonyl reductase 1
CCNT1 cyclin T1
CEP85 centrosomal protein 85kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
DBF4 DBF4 zinc finger
DDIT3 DNA-damage-inducible transcript 3
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DLL3 delta-like 3 (Drosophila)
DPH2 DPH2 homolog (S. cerevisiae)
DRG1 developmentally regulated GTP binding protein 1
ELP3 elongator acetyltransferase complex subunit 3
EMC9 ER membrane protein complex subunit 9
EPN3 epsin 3
ERCC3 excision repair cross-complementation group 3
FDXR ferredoxin reductase
GBAP1 glucosidase, beta, acid pseudogene 1
GMPPB GDP-mannose pyrophosphorylase B
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
GRPR gastrin-releasing peptide receptor
GSTZ1 glutathione S-transferase zeta 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HMBOX1 homeobox containing 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMHA1 histocompatibility (minor) HA-1
HOXB13 homeobox B13
HRAS Harvey rat sarcoma viral oncogene homolog
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL26 kelch-like family member 26
KRT86 keratin 86, type II
LAS1L LAS1-like (S. cerevisiae)
LRRC20 leucine rich repeat containing 20
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARC1 mitochondrial amidoxime reducing component 1
MPDU1 mannose-P-dolichol utilization defect 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MPV17 MpV17 mitochondrial inner membrane protein
MYO19 myosin XIX
NAGA N-acetylgalactosaminidase, alpha-
NVL nuclear VCP-like
OXA1L oxidase (cytochrome c) assembly 1-like
PAAF1 proteasomal ATPase-associated factor 1
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PARG poly (ADP-ribose) glycohydrolase
PCDHGB5 protocadherin gamma subfamily B, 5
PGM3 phosphoglucomutase 3
POU2F1 POU class 2 homeobox 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP4C protein phosphatase 4, catalytic subunit
PRPH peripherin
PSAT1 phosphoserine aminotransferase 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB17 RAB17, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A6 S100 calcium binding protein A6
SARS seryl-tRNA synthetase
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SETD1B SET domain containing 1B
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SF3B5 splicing factor 3b, subunit 5, 10kDa
SLC12A9 solute carrier family 12, member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMYD5 SMYD family member 5
TICAM1 toll-like receptor adaptor molecule 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM230 transmembrane protein 230
TNNT1 troponin T type 1 (skeletal, slow)
TRAIP TRAF interacting protein
TRAPPC12 trafficking protein particle complex 12
TRIM21 tripartite motif containing 21
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC1 tetratricopeptide repeat domain 1
TUSC2 tumor suppressor candidate 2
TWSG1 twisted gastrulation BMP signaling modulator 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZC3H3 zinc finger CCCH-type containing 3
ZFHX4 zinc finger homeobox 4
ZFP30 ZFP30 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF211 zinc finger protein 211
ZNF32 zinc finger protein 32
ZNF580 zinc finger protein 580
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN9 zinc finger and SCAN domain containing 9