| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the dienestrol-3448 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| BCL2A1 | BCL2-related protein A1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CD83 | CD83 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL1A1 | collagen, type I, alpha 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EXPH5 | exophilin 5 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALK2 | galactokinase 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNRHR | gonadotropin-releasing hormone receptor |
| HBEGF | heparin-binding EGF-like growth factor |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4E | histone cluster 1, H4e |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOXC10 | homeobox C10 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFT140 | intraflagellar transport 140 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL2RG | interleukin 2 receptor, gamma |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| LAMB4 | laminin, beta 4 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LAT2 | linker for activation of T cells family, member 2 |
| LHX6 | LIM homeobox 6 |
| LIF | leukemia inhibitory factor |
| LRRC17 | leucine rich repeat containing 17 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MPZ | myelin protein zero |
| MST1 | macrophage stimulating 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NME5 | NME/NM23 family member 5 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLAUR | plasminogen activator, urokinase receptor |
| PRKCE | protein kinase C, epsilon |
| PVR | poliovirus receptor |
| RFXAP | regulatory factor X-associated protein |
| RGS2 | regulator of G-protein signaling 2 |
| RPL18 | ribosomal protein L18 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SFTPB | surfactant protein B |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SMOX | spermine oxidase |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPRR1A | small proline-rich protein 1A |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYMPK | symplekin |
| TAZ | tafazzin |
| TCHH | trichohyalin |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM212 | transmembrane protein 212 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| UCN | urocortin |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF10 | zinc finger protein 10 |
| ZNF329 | zinc finger protein 329 |
| ZNF440 | zinc finger protein 440 |
| ZNF442 | zinc finger protein 442 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| AZI2 | 5-azacytidine induced 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BAK1 | BCL2-antagonist/killer 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5AR2 | complement component 5a receptor 2 |
| CAPN15 | calpain 15 |
| CASD1 | CAS1 domain containing 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNJ | cyclin J |
| CENPT | centromere protein T |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLDN9 | claudin 9 |
| CLMN | calmin (calponin-like, transmembrane) |
| COL9A2 | collagen, type IX, alpha 2 |
| COPS7B | COP9 signalosome subunit 7B |
| CST6 | cystatin E/M |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| FAM169A | family with sequence similarity 169, member A |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GHR | growth hormone receptor |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IRF6 | interferon regulatory factor 6 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIF13B | kinesin family member 13B |
| LIMA1 | LIM domain and actin binding 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP9 | microtubule-associated protein 9 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MED9 | mediator complex subunit 9 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MPDZ | multiple PDZ domain protein |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NEK11 | NIMA-related kinase 11 |
| NUBPL | nucleotide binding protein-like |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKX | protein kinase, X-linked |
| PROS1 | protein S (alpha) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB5B | RAB5B, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SP1 | Sp1 transcription factor |
| SSFA2 | sperm specific antigen 2 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYNJ2BP | synaptojanin 2 binding protein |
| TBP | TATA box binding protein |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THOP1 | thimet oligopeptidase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC5 | transmembrane channel-like 5 |
| TMEM104 | transmembrane protein 104 |
| TMEM135 | transmembrane protein 135 |
| TMEM62 | transmembrane protein 62 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOM1 | target of myb1 (chicken) |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM45 | tripartite motif containing 45 |
| TUBA3C | tubulin, alpha 3c |
| VASH2 | vasohibin 2 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF480 | zinc finger protein 480 |
| ZNF574 | zinc finger protein 574 |
