| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the diethylcarbamazine-7425 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| AZI2 | 5-azacytidine induced 2 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCL9 | B-cell CLL/lymphoma 9 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CEP170 | centrosomal protein 170kDa |
| CEP72 | centrosomal protein 72kDa |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| CUL2 | cullin 2 |
| CUL4B | cullin 4B |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EED | embryonic ectoderm development |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
| EIF5B | eukaryotic translation initiation factor 5B |
| FAM65A | family with sequence similarity 65, member A |
| FECH | ferrochelatase |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLOT1 | flotillin 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIPK3 | homeodomain interacting protein kinase 3 |
| IFT22 | intraflagellar transport 22 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KDM5A | lysine (K)-specific demethylase 5A |
| KDM6A | lysine (K)-specific demethylase 6A |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC399491 | |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPDZ | multiple PDZ domain protein |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MVB12B | multivesicular body subunit 12B |
| N4BP3 | NEDD4 binding protein 3 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLK4 | polo-like kinase 4 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDX2 | peroxiredoxin 2 |
| PRKCI | protein kinase C, iota |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RANBP2 | RAN binding protein 2 |
| RANBP3 | RAN binding protein 3 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RBL2 | retinoblastoma-like 2 |
| RBM48 | RNA binding motif protein 48 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPS2 | ribosomal protein S2 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SETD4 | SET domain containing 4 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STAG3 | stromal antigen 3 |
| STK17B | serine/threonine kinase 17b |
| TANK | TRAF family member-associated NFKB activator |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TESK1 | testis-specific kinase 1 |
| TGFB3 | transforming growth factor, beta 3 |
| THBD | thrombomodulin |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TMEM180 | transmembrane protein 180 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRAIP | TRAF interacting protein |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WDR55 | WD repeat domain 55 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZNF141 | zinc finger protein 141 |
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALPK1 | alpha-kinase 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC6 | armadillo repeat containing 6 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CAPN5 | calpain 5 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC64 | coiled-coil domain containing 64 |
| CCDC85C | coiled-coil domain containing 85C |
| CENPO | centromere protein O |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CSTA | cystatin A (stefin A) |
| DALRD3 | DALR anticodon binding domain containing 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DMTN | dematin actin binding protein |
| DYSF | dysferlin |
| EDAR | ectodysplasin A receptor |
| FAM131A | family with sequence similarity 131, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUZ | fuzzy planar cell polarity protein |
| FZD4 | frizzled class receptor 4 |
| GATA4 | GATA binding protein 4 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR27 | G protein-coupled receptor 27 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4J | histone cluster 1, H4j |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KRT13 | keratin 13, type I |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC20 | leucine rich repeat containing 20 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP1S | microtubule-associated protein 1S |
| MCC | mutated in colorectal cancers |
| MCOLN1 | mucolipin 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| NDRG4 | NDRG family member 4 |
| NINL | ninein-like |
| NPFFR1 | neuropeptide FF receptor 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PCBP4 | poly(rC) binding protein 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB30 | RAB30, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RECQL4 | RecQ protein-like 4 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF123 | ring finger protein 123 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPS15A | ribosomal protein S15a |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| S100A9 | S100 calcium binding protein A9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SNAI2 | snail family zinc finger 2 |
| SPATA2L | spermatogenesis associated 2-like |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TPCN1 | two pore segment channel 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VEGFB | vascular endothelial growth factor B |
| VPS9D1 | VPS9 domain containing 1 |
| WDR25 | WD repeat domain 25 |
| WDR60 | WD repeat domain 60 |
| ZNF219 | zinc finger protein 219 |
| ZNF324 | zinc finger protein 324 |
| ZNF329 | zinc finger protein 329 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
