diethylstilbestrol-3812 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the diethylstilbestrol-3812 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
AGRP agouti related neuropeptide
ALB albumin
ARTN artemin
ATF5 activating transcription factor 5
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP2 bone morphogenetic protein 2
C22ORF24 chromosome 22 open reading frame 24
CA14 carbonic anhydrase XIV
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCL16 chemokine (C-C motif) ligand 16
CD6 CD6 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL14A1 collagen, type XIV, alpha 1
CRYAB crystallin, alpha B
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CXCR2 chemokine (C-X-C motif) receptor 2
DGKQ diacylglycerol kinase, theta 110kDa
DIO2 deiodinase, iodothyronine, type II
DMP1 dentin matrix acidic phosphoprotein 1
DOCK6 dedicator of cytokinesis 6
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP13 dual specificity phosphatase 13
FAIM2 Fas apoptotic inhibitory molecule 2
FGF4 fibroblast growth factor 4
GAL3ST4 galactose-3-O-sulfotransferase 4
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRIP2 glutamate receptor interacting protein 2
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GZMK granzyme K (granzyme 3; tryptase II)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IMPG2 interphotoreceptor matrix proteoglycan 2
JUND jun D proto-oncogene
KHK ketohexokinase (fructokinase)
KLF1 Kruppel-like factor 1 (erythroid)
LCAT lecithin-cholesterol acyltransferase
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LINC00115 long intergenic non-protein coding RNA 115
LTB4R leukotriene B4 receptor
LTBP4 latent transforming growth factor beta binding protein 4
MVB12B multivesicular body subunit 12B
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NDOR1 NADPH dependent diflavin oxidoreductase 1
NDP Norrie disease (pseudoglioma)
NLGN4X neuroligin 4, X-linked
NOP14-AS1 NOP14 antisense RNA 1
NOP16 NOP16 nucleolar protein
NOVA2 neuro-oncological ventral antigen 2
NPTX2 neuronal pentraxin II
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFB platelet-derived growth factor beta polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PON1 paraoxonase 1
POU2F2 POU class 2 homeobox 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAG1 recombination activating gene 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RIMS1 regulating synaptic membrane exocytosis 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
S100A5 S100 calcium binding protein A5
SAMD4A sterile alpha motif domain containing 4A
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHOX2 short stature homeobox 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SP110 SP110 nuclear body protein
SPTBN5 spectrin, beta, non-erythrocytic 5
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSX3 synovial sarcoma, X breakpoint 3
SULF1 sulfatase 1
SULT4A1 sulfotransferase family 4A, member 1
SYMPK symplekin
SYT12 synaptotagmin XII
TBC1D2 TBC1 domain family, member 2
TBCD tubulin folding cofactor D
TEX14 testis expressed 14
THY1 Thy-1 cell surface antigen
TMPRSS11D transmembrane protease, serine 11D
TRO trophinin
TTLL1 tubulin tyrosine ligase-like family member 1
UBXN1 UBX domain protein 1
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VAV3 vav 3 guanine nucleotide exchange factor
WDR25 WD repeat domain 25

decreased expression

Symbol Name
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AFF4 AF4/FMR2 family, member 4
AGMAT agmatine ureohydrolase (agmatinase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARMCX4 armadillo repeat containing, X-linked 4
ART1 ADP-ribosyltransferase 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATG10 autophagy related 10
BAHD1 bromo adjacent homology domain containing 1
BBC3 BCL2 binding component 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CA11 carbonic anhydrase XI
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC132 coiled-coil domain containing 132
CCNK cyclin K
CEP295 centrosomal protein 295kDa
CHM choroideremia (Rab escort protein 1)
CLDN8 claudin 8
CLEC4E C-type lectin domain family 4, member E
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYTH3 cytohesin 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DENND4A DENN/MADD domain containing 4A
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EDN1 endothelin 1
EML4 echinoderm microtubule associated protein like 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EREG epiregulin
EXD3 exonuclease 3'-5' domain containing 3
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FKBP5 FK506 binding protein 5
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FSHB follicle stimulating hormone, beta polypeptide
GEMIN8 gem (nuclear organelle) associated protein 8
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPNMB glycoprotein (transmembrane) nmb
GPR75 G protein-coupled receptor 75
GRB7 growth factor receptor-bound protein 7
INO80D INO80 complex subunit D
KCTD17 potassium channel tetramerization domain containing 17
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
LATS1 large tumor suppressor kinase 1
LGALS4 lectin, galactoside-binding, soluble, 4
LMAN1 lectin, mannose-binding, 1
LOC100287590 uncharacterized LOC100287590
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MATN3 matrilin 3
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MGC12488
MILR1 mast cell immunoglobulin-like receptor 1
MN1 meningioma (disrupted in balanced translocation) 1
MNX1 motor neuron and pancreas homeobox 1
MTCP1 mature T-cell proliferation 1
NEUROD1 neuronal differentiation 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OLFML2B olfactomedin-like 2B
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARPBP PARP1 binding protein
PGPEP1 pyroglutamyl-peptidase I
PICK1 protein interacting with PRKCA 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB40AL RAB40A, member RAS oncogene family-like
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RLN1 relaxin 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC16A6 solute carrier family 16, member 6
SLMO1 slowmo homolog 1 (Drosophila)
ST20 suppressor of tumorigenicity 20
STXBP5L syntaxin binding protein 5-like
TBC1D17 TBC1 domain family, member 17
TCEAL2 transcription elongation factor A (SII)-like 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TTC30A tetratricopeptide repeat domain 30A
TUBA4B tubulin, alpha 4b
TXK TXK tyrosine kinase
VNN1 vanin 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZFHX2 zinc finger homeobox 2
ZFHX3 zinc finger homeobox 3
ZNF334 zinc finger protein 334
ZNF516 zinc finger protein 516
ZNF529 zinc finger protein 529