diethylstilbestrol-3895 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the diethylstilbestrol-3895 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
ADM adrenomedullin
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ARR3 arrestin 3, retinal (X-arrestin)
ASPH aspartate beta-hydroxylase
ATF3 activating transcription factor 3
BAX BCL2-associated X protein
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
CALB1 calbindin 1, 28kDa
CDC25C cell division cycle 25C
CNTD2 cyclin N-terminal domain containing 2
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DDIT3 DNA-damage-inducible transcript 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DPY19L2P2 DPY19L2 pseudogene 2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR3 early growth response 3
ERO1LB ERO1-like beta (S. cerevisiae)
ETV5 ets variant 5
FAM46C family with sequence similarity 46, member C
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GRK5 G protein-coupled receptor kinase 5
GZMK granzyme K (granzyme 3; tryptase II)
HBEGF heparin-binding EGF-like growth factor
HIRA histone cell cycle regulator
HIST1H4H histone cluster 1, H4h
HMOX1 heme oxygenase 1
HOXD11 homeobox D11
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL23A interleukin 23, alpha subunit p19
INHBE inhibin, beta E
JUN jun proto-oncogene
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLF13 Kruppel-like factor 13
KRT6B keratin 6B, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K7 mitogen-activated protein kinase kinase 7
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCAM melanoma cell adhesion molecule
MEF2D myocyte enhancer factor 2D
MMP11 matrix metallopeptidase 11
NDNF neuron-derived neurotrophic factor
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRDE2 NRDE-2, necessary for RNA interference, domain containing
OVOL1 ovo-like zinc finger 1
PCDHA5 protocadherin alpha 5
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE8B phosphodiesterase 8B
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB40C RAB40C, member RAS oncogene family
RASAL2 RAS protein activator like 2
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RIOK3 RIO kinase 3
RNASE4 ribonuclease, RNase A family, 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SNAI1 snail family zinc finger 1
SOX15 SRY (sex determining region Y)-box 15
SOX9 SRY (sex determining region Y)-box 9
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGN serglycin
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SUN1 Sad1 and UNC84 domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TEX14 testis expressed 14
TGFA transforming growth factor, alpha
THBS1 thrombospondin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TTLL7 tubulin tyrosine ligase-like family member 7
WASL Wiskott-Aldrich syndrome-like
ZNF224 zinc finger protein 224
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSF2 acyl-CoA synthetase family member 2
ADRA2C adrenoceptor alpha 2C
ALOX12 arachidonate 12-lipoxygenase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCO1 beta-carotene oxygenase 1
BLNK B-cell linker
C2ORF27A chromosome 2 open reading frame 27A
CAPN5 calpain 5
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC64 coiled-coil domain containing 64
CCDC69 coiled-coil domain containing 69
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CNGB3 cyclic nucleotide gated channel beta 3
CRIP1 cysteine-rich protein 1 (intestinal)
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DEPDC5 DEP domain containing 5
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD1 dopamine receptor D1
FADS2 fatty acid desaturase 2
FKRP fukutin related protein
GHR growth hormone receptor
GK3P glycerol kinase 3 pseudogene
GLB1L galactosidase, beta 1-like
GPR176 G protein-coupled receptor 176
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HDAC5 histone deacetylase 5
HIST1H3E histone cluster 1, H3e
HOXC4 homeobox C4
HOXC5 homeobox C5
IGFBP6 insulin-like growth factor binding protein 6
IGSF1 immunoglobulin superfamily, member 1
IQSEC2 IQ motif and Sec7 domain 2
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KLK8 kallikrein-related peptidase 8
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NPPA natriuretic peptide A
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PICK1 protein interacting with PRKCA 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PORCN porcupine homolog (Drosophila)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PTPRS protein tyrosine phosphatase, receptor type, S
PVRL3 poliovirus receptor-related 3
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SERGEF secretion regulating guanine nucleotide exchange factor
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC12A9 solute carrier family 12, member 9
SLC22A14 solute carrier family 22, member 14
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMIM14 small integral membrane protein 14
SNTA1 syntrophin, alpha 1
SPAG4 sperm associated antigen 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STON1 stonin 1
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D19 TBC1 domain family, member 19
TCP10 t-complex 10
TFDP3 transcription factor Dp family, member 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR3 transforming growth factor, beta receptor III
TPRA1 transmembrane protein, adipocyte asscociated 1
TUBA3C tubulin, alpha 3c
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
WNT16 wingless-type MMTV integration site family, member 16
ZNF134 zinc finger protein 134
ZNF350 zinc finger protein 350
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862