diethylstilbestrol-4369 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the diethylstilbestrol-4369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ALOXE3 arachidonate lipoxygenase 3
ANG angiogenin, ribonuclease, RNase A family, 5
ANO1 anoctamin 1, calcium activated chloride channel
ART1 ADP-ribosyltransferase 1
ATF3 activating transcription factor 3
BIRC3 baculoviral IAP repeat containing 3
CADM3 cell adhesion molecule 3
CALB1 calbindin 1, 28kDa
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCR7 chemokine (C-C motif) receptor 7
CDK19 cyclin-dependent kinase 19
CEP112 centrosomal protein 112kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL21A1 collagen, type XXI, alpha 1
CRISP2 cysteine-rich secretory protein 2
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPY19L2P2 DPY19L2 pseudogene 2
DRD1 dopamine receptor D1
EGR1 early growth response 1
EGR3 early growth response 3
FAM46C family with sequence similarity 46, member C
FAM63B family with sequence similarity 63, member B
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXL1 forkhead box L1
FRMD8 FERM domain containing 8
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
G6PC2 glucose-6-phosphatase, catalytic, 2
GEM GTP binding protein overexpressed in skeletal muscle
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HBEGF heparin-binding EGF-like growth factor
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGL immunoglobulin lambda locus
IL18BP interleukin 18 binding protein
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
JUN jun proto-oncogene
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
LAT2 linker for activation of T cells family, member 2
LDB3 LIM domain binding 3
LGSN lengsin, lens protein with glutamine synthetase domain
LMOD1 leiomodin 1 (smooth muscle)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP25 matrix metallopeptidase 25
MORN1 MORN repeat containing 1
MRPL41 mitochondrial ribosomal protein L41
MUC5B mucin 5B, oligomeric mucus/gel-forming
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPY2R neuropeptide Y receptor Y2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUP188 nucleoporin 188kDa
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE4C phosphodiesterase 4C, cAMP-specific
PGR progesterone receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCD1 phospholipase C, delta 1
PSG6 pregnancy specific beta-1-glycoprotein 6
RAB6B RAB6B, member RAS oncogene family
REEP2 receptor accessory protein 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGK1 serum/glucocorticoid regulated kinase 1
SHOX2 short stature homeobox 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC43A3 solute carrier family 43, member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO2A1 solute carrier organic anion transporter family, member 2A1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TDRD12 tudor domain containing 12
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNS1 tensin 1
USP2 ubiquitin specific peptidase 2
USP53 ubiquitin specific peptidase 53
VLDLR very low density lipoprotein receptor
ZC3H13 zinc finger CCCH-type containing 13
ZFP64 ZFP64 zinc finger protein
ZNF235 zinc finger protein 235
ZNF280A zinc finger protein 280A
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BIRC7 baculoviral IAP repeat containing 7
C10ORF95 chromosome 10 open reading frame 95
C11ORF21 chromosome 11 open reading frame 21
C2ORF44 chromosome 2 open reading frame 44
CDH18 cadherin 18, type 2
CDK3 cyclin-dependent kinase 3
CFHR4 complement factor H-related 4
CLSTN2 calsyntenin 2
CRY2 cryptochrome circadian clock 2
CUL9 cullin 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DNAH17 dynein, axonemal, heavy chain 17
DNASE1L2 deoxyribonuclease I-like 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
FBRS fibrosin
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FOXI1 forkhead box I1
GAMT guanidinoacetate N-methyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR143 G protein-coupled receptor 143
GREB1L growth regulation by estrogen in breast cancer-like
HAMP hepcidin antimicrobial peptide
HCAR3 hydroxycarboxylic acid receptor 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIST1H2AK histone cluster 1, H2ak
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXD11 homeobox D11
ISL1 ISL LIM homeobox 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIFC3 kinesin family member C3
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAX1 lymphocyte transmembrane adaptor 1
LGALS9 lectin, galactoside-binding, soluble, 9
LOC157562 uncharacterized LOC157562
LOC390998 ribosomal protein L10 pseudogene
LRP2 low density lipoprotein receptor-related protein 2
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAL mal, T-cell differentiation protein
MFAP2 microfibrillar-associated protein 2
MRPS18C mitochondrial ribosomal protein S18C
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NNAT neuronatin
NT5DC3 5'-nucleotidase domain containing 3
NT5E 5'-nucleotidase, ecto (CD73)
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAOX polyamine oxidase (exo-N4-amino)
PAX9 paired box 9
PCDH17 protocadherin 17
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PICK1 protein interacting with PRKCA 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
POU3F2 POU class 3 homeobox 2
PP14571 uncharacterized LOC100130449
PRF1 perforin 1 (pore forming protein)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFXAP regulatory factor X-associated protein
RPA4 replication protein A4, 30kDa
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
S100A7 S100 calcium binding protein A7
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
STAG3 stromal antigen 3
STON1 stonin 1
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRIM68 tripartite motif containing 68
UCN urocortin
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFHX4 zinc finger homeobox 4
ZIC3 Zic family member 3
ZNF510 zinc finger protein 510
ZNF639 zinc finger protein 639
ZNF696 zinc finger protein 696
ZNF767P zinc finger family member 767, pseudogene