| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the difenidol-2374 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| AGTR2 | angiotensin II receptor, type 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APP | amyloid beta (A4) precursor protein |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATF6B | activating transcription factor 6 beta |
| B9D1 | B9 protein domain 1 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C1RL | complement component 1, r subcomponent-like |
| CAT | catalase |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD58 | CD58 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDK3 | cyclin-dependent kinase 3 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| COL10A1 | collagen, type X, alpha 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DMWD | dystrophia myotonica, WD repeat containing |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DTNA | dystrobrevin, alpha |
| ENO3 | enolase 3 (beta, muscle) |
| F12 | coagulation factor XII (Hageman factor) |
| FGB | fibrinogen beta chain |
| FOXO1 | forkhead box O1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GPR162 | G protein-coupled receptor 162 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HOXA1 | homeobox A1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IL33R | interleukin 33 receptor |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF13B | kinesin family member 13B |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LCT | lactase |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCOLN1 | mucolipin 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MKL2 | MKL/myocardin-like 2 |
| NDNF | neuron-derived neurotrophic factor |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NTM | neurotrimin |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDCL | phosducin-like |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLEK2 | pleckstrin 2 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKCQ | protein kinase C, theta |
| PRX | periaxin |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBKS | ribokinase |
| RBM26 | RNA binding motif protein 26 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like |
| RECQL5 | RecQ protein-like 5 |
| RHBDD3 | rhomboid domain containing 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPH3A | rabphilin 3A |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SPRR1B | small proline-rich protein 1B |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM144 | transmembrane protein 144 |
| TSC22D4 | TSC22 domain family, member 4 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF177 | zinc finger protein 177 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AMT | aminomethyltransferase |
| ANXA2P2 | annexin A2 pseudogene 2 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ASPN | asporin |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CAPN5 | calpain 5 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD82 | CD82 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEP295 | centrosomal protein 295kDa |
| CPTP | ceramide-1-phosphate transfer protein |
| CTSK | cathepsin K |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOC2A | double C2-like domains, alpha |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENG | endoglin |
| ERCC4 | excision repair cross-complementation group 4 |
| ERF | Ets2 repressor factor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM102A | family with sequence similarity 102, member A |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FAM163A | family with sequence similarity 163, member A |
| FN3KRP | fructosamine 3 kinase related protein |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR22 | G protein-coupled receptor 22 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HOPX | HOP homeobox |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP6D1 | MAP6 domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MTA2 | metastasis associated 1 family, member 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MYL5 | myosin, light chain 5, regulatory |
| NAG18 | NAG18 mRNA |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PADI1 | peptidyl arginine deiminase, type I |
| PANX1 | pannexin 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PDZD7 | PDZ domain containing 7 |
| PIR | pirin (iron-binding nuclear protein) |
| PLS1 | plastin 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POR | P450 (cytochrome) oxidoreductase |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAF2 | PRA1 domain family, member 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SH2D4A | SH2 domain containing 4A |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNX16 | sorting nexin 16 |
| SPIN1 | spindlin 1 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TESK2 | testis-specific kinase 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM156 | transmembrane protein 156 |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TOR4A | torsin family 4, member A |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WASF3 | WAS protein family, member 3 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF134 | zinc finger protein 134 |
| ZNF675 | zinc finger protein 675 |
| ZNF696 | zinc finger protein 696 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
