| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the difenidol-7406 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| APOE | apolipoprotein E |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BMP6 | bone morphogenetic protein 6 |
| C2CD2L | C2CD2-like |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNO | cyclin O |
| CD70 | CD70 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD83 | CD83 molecule |
| CDK10 | cyclin-dependent kinase 10 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| EFNB3 | ephrin-B3 |
| EGFR | epidermal growth factor receptor |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EPHB4 | EPH receptor B4 |
| ESR1 | estrogen receptor 1 |
| FAAH | fatty acid amide hydrolase |
| FADS3 | fatty acid desaturase 3 |
| FAM65A | family with sequence similarity 65, member A |
| FGF4 | fibroblast growth factor 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALR3 | galanin receptor 3 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPX2 | glutathione peroxidase 2 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HSF1 | heat shock transcription factor 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFT38 | intraflagellar transport 38 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL11 | interleukin 11 |
| IL17RA | interleukin 17 receptor A |
| IL4R | interleukin 4 receptor |
| IRF5 | interferon regulatory factor 5 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| JMJD4 | jumonji domain containing 4 |
| KIAA0485 | uncharacterized LOC57235 |
| KIF3C | kinesin family member 3C |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LMNA | lamin A/C |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PALM | paralemmin |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH12 | protocadherin 12 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PCDHGC3 | protocadherin gamma subfamily C, 3 |
| PODNL1 | podocan-like 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRY | PTPN13-like, Y-linked |
| PTN | pleiotrophin |
| QSER1 | glutamine and serine rich 1 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAP2B | RAP2B, member of RAS oncogene family |
| RNF39 | ring finger protein 39 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIRT3 | sirtuin 3 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SP1 | Sp1 transcription factor |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| STK4 | serine/threonine kinase 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYNGR1 | synaptogyrin 1 |
| TAC3 | tachykinin 3 |
| TLN2 | talin 2 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| USB1 | U6 snRNA biogenesis 1 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAX | BCL2-associated X protein |
| BEX4 | brain expressed, X-linked 4 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC15 | coiled-coil domain containing 15 |
| CEP83 | centrosomal protein 83kDa |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLK2 | CDC-like kinase 2 |
| COQ6 | coenzyme Q6 monooxygenase |
| CTSV | cathepsin V |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DGKD | diacylglycerol kinase, delta 130kDa |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCF | Fanconi anemia, complementation group F |
| FBRS | fibrosin |
| FHOD1 | formin homology 2 domain containing 1 |
| GAN | gigaxonin |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR19 | G protein-coupled receptor 19 |
| GTPBP2 | GTP binding protein 2 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIRA | histone cell cycle regulator |
| HIRIP3 | HIRA interacting protein 3 |
| HMBOX1 | homeobox containing 1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IFT46 | intraflagellar transport 46 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IRF9 | interferon regulatory factor 9 |
| KIAA0125 | KIAA0125 |
| KIFC1 | kinesin family member C1 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMNB1 | lamin B1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MBTD1 | mbt domain containing 1 |
| MGA | MGA, MAX dimerization protein |
| MTCL1 | microtubule crosslinking factor 1 |
| MUTYH | mutY homolog |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POR | P450 (cytochrome) oxidoreductase |
| PRKX | protein kinase, X-linked |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| RWDD2A | RWD domain containing 2A |
| RWDD3 | RWD domain containing 3 |
| SALL2 | spalt-like transcription factor 2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SFT2D2 | SFT2 domain containing 2 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNX16 | sorting nexin 16 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STBD1 | starch binding domain 1 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYNJ2BP | synaptojanin 2 binding protein |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TCTA | T-cell leukemia translocation altered |
| TEAD3 | TEA domain family member 3 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRIM25 | tripartite motif containing 25 |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC31 | tetratricopeptide repeat domain 31 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF219 | zinc finger protein 219 |
| ZNF8 | zinc finger protein 8 |
| ZW10 | zw10 kinetochore protein |
