| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the difenidol-7447 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| AFAP1 | actin filament associated protein 1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BTG2 | BTG family, member 2 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CCDC93 | coiled-coil domain containing 93 |
| CD44 | CD44 molecule (Indian blood group) |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK20 | cyclin-dependent kinase 20 |
| CEP104 | centrosomal protein 104kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CTAGE5 | CTAGE family, member 5 |
| CTSZ | cathepsin Z |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOK4 | docking protein 4 |
| DVL1 | dishevelled segment polarity protein 1 |
| ECE1 | endothelin converting enzyme 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPS8L3 | EPS8-like 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM65A | family with sequence similarity 65, member A |
| FBXO2 | F-box protein 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FLOT1 | flotillin 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAB1 | GRB2-associated binding protein 1 |
| GRPR | gastrin-releasing peptide receptor |
| GSPT1 | G1 to S phase transition 1 |
| GSTM4 | glutathione S-transferase mu 4 |
| HABP4 | hyaluronan binding protein 4 |
| HBEGF | heparin-binding EGF-like growth factor |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HDLBP | high density lipoprotein binding protein |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL22 | interleukin 22 |
| ING4 | inhibitor of growth family, member 4 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KDM6A | lysine (K)-specific demethylase 6A |
| KLHL24 | kelch-like family member 24 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIMCH1 | LIM and calponin homology domains 1 |
| MAP4 | microtubule-associated protein 4 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NDRG2 | NDRG family member 2 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NOX1 | NADPH oxidase 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PLAC1 | placenta-specific 1 |
| PLXNB1 | plexin B1 |
| PODNL1 | podocan-like 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PSAT1 | phosphoserine aminotransferase 1 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB40C | RAB40C, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| RBM19 | RNA binding motif protein 19 |
| RECQL5 | RecQ protein-like 5 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN3 | Ras and Rab interactor 3 |
| RPL10 | ribosomal protein L10 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RTN2 | reticulon 2 |
| RUNX1 | runt-related transcription factor 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STIM1 | stromal interaction molecule 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TMC7 | transmembrane channel-like 7 |
| TREX1 | three prime repair exonuclease 1 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TXNL4A | thioredoxin-like 4A |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR55 | WD repeat domain 55 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| YY2 | YY2 transcription factor |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFX | zinc finger protein, X-linked |
| ZNF442 | zinc finger protein 442 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| ATRN | attractin |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC186 | coiled-coil domain containing 186 |
| CENPQ | centromere protein Q |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CIC | capicua transcriptional repressor |
| CPTP | ceramide-1-phosphate transfer protein |
| CTAGE9 | CTAGE family, member 9 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DEAF1 | DEAF1 transcription factor |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| FBXO46 | F-box protein 46 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GPATCH3 | G patch domain containing 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GPX2 | glutathione peroxidase 2 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H2BI | histone cluster 1, H2bi |
| IL15RA | interleukin 15 receptor, alpha |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IRF9 | interferon regulatory factor 9 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LINS | lines homolog (Drosophila) |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| METTL2B | methyltransferase like 2B |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MITF | microphthalmia-associated transcription factor |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MSMB | microseminoprotein, beta- |
| MT1E | metallothionein 1E |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTMR11 | myotubularin related protein 11 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NMU | neuromedin U |
| PC | pyruvate carboxylase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPCDC | phosphopantothenoylcysteine decarboxylase |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR3 | proline rich 3 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP1 | Sp1 transcription factor |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| TCTN1 | tectonic family member 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM104 | transmembrane protein 104 |
| TMEM180 | transmembrane protein 180 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TROAP | trophinin associated protein |
| UFSP2 | UFM1-specific peptidase 2 |
| ULBP2 | UL16 binding protein 2 |
| VASP | vasodilator-stimulated phosphoprotein |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF219 | zinc finger protein 219 |
| ZNF286A | zinc finger protein 286A |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF669 | zinc finger protein 669 |
| ZXDC | ZXD family zinc finger C |
