diflunisal-1908 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the diflunisal-1908 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACBD4 acyl-CoA binding domain containing 4
ADRBK1 adrenergic, beta, receptor kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF5 activating transcription factor 5
B3GAT3 beta-1,3-glucuronyltransferase 3
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C16ORF59 chromosome 16 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
C21ORF33 chromosome 21 open reading frame 33
C7ORF26 chromosome 7 open reading frame 26
C9ORF16 chromosome 9 open reading frame 16
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHMP1A charged multivesicular body protein 1A
CIZ1 CDKN1A interacting zinc finger protein 1
COL13A1 collagen, type XIII, alpha 1
DGCR8 DGCR8 microprocessor complex subunit
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DTX4 deltex 4, E3 ubiquitin ligase
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
FAM65A family with sequence similarity 65, member A
FBXL5 F-box and leucine-rich repeat protein 5
FBXO31 F-box protein 31
FOLR1 folate receptor 1 (adult)
FOXO1 forkhead box O1
FXYD3 FXYD domain containing ion transport regulator 3
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLG1 golgi glycoprotein 1
GLRX3 glutaredoxin 3
HFE hemochromatosis
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIRIP3 HIRA interacting protein 3
HIST1H2AE histone cluster 1, H2ae
HOXB2 homeobox B2
HRH1 histamine receptor H1
IGKV1D-13 immunoglobulin kappa variable 1D-13
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD14 potassium channel tetramerization domain containing 14
MAPK10 mitogen-activated protein kinase 10
MYL9 myosin, light chain 9, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUPR1 nuclear protein, transcriptional regulator, 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PBX2 pre-B-cell leukemia homeobox 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33B RAB33B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RARG retinoic acid receptor, gamma
RASL11B RAS-like, family 11, member B
RCAN1 regulator of calcineurin 1
RECQL5 RecQ protein-like 5
RGR retinal G protein coupled receptor
RGS16 regulator of G-protein signaling 16
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SAMD4A sterile alpha motif domain containing 4A
SAMHD1 SAM domain and HD domain 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERTAD3 SERTA domain containing 3
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMC2 structural maintenance of chromosomes 2
SNPH syntaphilin
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STX6 syntaxin 6
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D17 TBC1 domain family, member 17
THTPA thiamine triphosphatase
TMEM80 transmembrane protein 80
TRAF4 TNF receptor-associated factor 4
TRIM58 tripartite motif containing 58
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSKU tsukushi, small leucine rich proteoglycan
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
WDR47 WD repeat domain 47
WIZ widely interspaced zinc finger motifs
WNT7A wingless-type MMTV integration site family, member 7A
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZMAT5 zinc finger, matrin-type 5
ZNF177 zinc finger protein 177
ZNF408 zinc finger protein 408
ZNF710 zinc finger protein 710
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
AHCTF1 AT hook containing transcription factor 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP5M1 adaptor-related protein complex 5, mu 1 subunit
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATF1 activating transcription factor 1
BAHD1 bromo adjacent homology domain containing 1
BCAS3 breast carcinoma amplified sequence 3
BCL2L13 BCL2-like 13 (apoptosis facilitator)
C2CD5 C2 calcium-dependent domain containing 5
C8ORF60 chromosome 8 open reading frame 60
CCNE1 cyclin E1
CEP85 centrosomal protein 85kDa
CETN3 centrin, EF-hand protein, 3
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHML choroideremia-like (Rab escort protein 2)
CHPF chondroitin polymerizing factor
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CISH cytokine inducible SH2-containing protein
CLGN calmegin
CNTD2 cyclin N-terminal domain containing 2
COMMD10 COMM domain containing 10
CPOX coproporphyrinogen oxidase
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXADR coxsackie virus and adenovirus receptor
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK1 dedicator of cytokinesis 1
EXOC1 exocyst complex component 1
FAM222B family with sequence similarity 222, member B
FAM35A family with sequence similarity 35, member A
FANCC Fanconi anemia, complementation group C
GALR3 galanin receptor 3
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
ITFG1 integrin alpha FG-GAP repeat containing 1
KIF20B kinesin family member 20B
KLF11 Kruppel-like factor 11
LIN7C lin-7 homolog C (C. elegans)
LMTK1 lemur tail kinase 1
LOC440434 aminopeptidase puromycin sensitive pseudogene
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC37A2 leucine rich repeat containing 37, member A2
LZTR1 leucine-zipper-like transcription regulator 1
MANSC1 MANSC domain containing 1
MB myoglobin
MEIS3P1 Meis homeobox 3 pseudogene 1
MFSD5 major facilitator superfamily domain containing 5
MNX1 motor neuron and pancreas homeobox 1
MOSPD3 motile sperm domain containing 3
MPHOSPH8 M-phase phosphoprotein 8
MRPL33 mitochondrial ribosomal protein L33
MT1HL1 metallothionein 1H-like 1
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
NXPH4 neurexophilin 4
PADI1 peptidyl arginine deiminase, type I
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCD1 phospholipase C, delta 1
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PTX3 pentraxin 3, long
PYCRL pyrroline-5-carboxylate reductase-like
PYGB phosphorylase, glycogen; brain
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RC3H2 ring finger and CCCH-type domains 2
RIPPLY3 ripply transcriptional repressor 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RSL24D1 ribosomal L24 domain containing 1
SAP30L SAP30-like
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3GL1 SH3-domain GRB2-like 1
SHROOM2 shroom family member 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM53 transmembrane protein 53
TOP2B topoisomerase (DNA) II beta 180kDa
TRIM5 tripartite motif containing 5
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TWSG1 twisted gastrulation BMP signaling modulator 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USP32 ubiquitin specific peptidase 32
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP6 ubiquitin specific peptidase 6
WASF1 WAS protein family, member 1
ZCCHC10 zinc finger, CCHC domain containing 10
ZHX2 zinc fingers and homeoboxes 2
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZMYM3 zinc finger, MYM-type 3
ZNF189 zinc finger protein 189
ZNF665 zinc finger protein 665