| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the diflunisal-4210 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| AIM1L | absent in melanoma 1-like |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ANGPT1 | angiopoietin 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG10 | autophagy related 10 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAGE | B melanoma antigen |
| BCAP29 | B-cell receptor-associated protein 29 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CD28 | CD28 molecule |
| CDH19 | cadherin 19, type 2 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CLEC1B | C-type lectin domain family 1, member B |
| CLEC4E | C-type lectin domain family 4, member E |
| CLIC5 | chloride intracellular channel 5 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTN1 | contactin 1 |
| CST4 | cystatin S |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DLX2 | distal-less homeobox 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DRD2 | dopamine receptor D2 |
| DSCR4 | Down syndrome critical region 4 |
| DST | dystonin |
| EPS8L1 | EPS8-like 1 |
| FAM106A | family with sequence similarity 106, member A |
| FRY | furry homolog (Drosophila) |
| FZD10 | frizzled class receptor 10 |
| GK2 | glycerol kinase 2 |
| GLRA1 | glycine receptor, alpha 1 |
| HFE | hemochromatosis |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL2 | interleukin 2 |
| IL6ST | interleukin 6 signal transducer |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC1720 | dihydrofolate reductase pseudogene |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble |
| METTL7A | methyltransferase like 7A |
| MPPE1 | metallophosphoesterase 1 |
| MUC3A | mucin 3A, cell surface associated |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NF1 | neurofibromin 1 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OLFM1 | olfactomedin 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTCH1 | patched 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PVR | poliovirus receptor |
| RAB36 | RAB36, member RAS oncogene family |
| RB1 | retinoblastoma 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS11 | regulator of G-protein signaling 11 |
| RHO | rhodopsin |
| RIN3 | Ras and Rab interactor 3 |
| RUNX1 | runt-related transcription factor 1 |
| SATB2 | SATB homeobox 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERHL2 | serine hydrolase-like 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SMAD4 | SMAD family member 4 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TAOK1 | TAO kinase 1 |
| TBX6 | T-box 6 |
| TLE4 | transducin-like enhancer of split 4 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| VCX2 | variable charge, X-linked 2 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADCY6 | adenylate cyclase 6 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C8A | complement component 8, alpha polypeptide |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CLDN1 | claudin 1 |
| CLDN15 | claudin 15 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CYBRD1 | cytochrome b reductase 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| E4F1 | E4F transcription factor 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FANCC | Fanconi anemia, complementation group C |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GMPR | guanosine monophosphate reductase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR3 | G protein-coupled receptor 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HDAC7 | histone deacetylase 7 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AK | histone cluster 1, H2ak |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL17RA | interleukin 17 receptor A |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KIAA1549L | KIAA1549-like |
| KLHL28 | kelch-like family member 28 |
| KRT86 | keratin 86, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC100287590 | uncharacterized LOC100287590 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LTC4S | leukotriene C4 synthase |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MB | myoglobin |
| MDFI | MyoD family inhibitor |
| METTL16 | methyltransferase like 16 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MTCP1 | mature T-cell proliferation 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MVP | major vault protein |
| MYO1E | myosin IE |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDRG4 | NDRG family member 4 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTOF | otoferlin |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| OTUD3 | OTU deubiquitinase 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDH12 | protocadherin 12 |
| PDE8B | phosphodiesterase 8B |
| PLBD1 | phospholipase B domain containing 1 |
| PLCD1 | phospholipase C, delta 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKX | protein kinase, X-linked |
| PROX1 | prospero homeobox 1 |
| RAPSN | receptor-associated protein of the synapse |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCPEP1 | serine carboxypeptidase 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPRYD7 | SPRY domain containing 7 |
| STEAP4 | STEAP family member 4 |
| TAGLN3 | transgelin 3 |
| TCTN2 | tectonic family member 2 |
| TMEM8B | transmembrane protein 8B |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UGT8 | UDP glycosyltransferase 8 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF215 | zinc finger protein 215 |
| ZNF34 | zinc finger protein 34 |
| ZNF711 | zinc finger protein 711 |
