| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the digitoxigenin-1339 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| AQP9 | aquaporin 9 |
| AREG | amphiregulin |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C18ORF25 | chromosome 18 open reading frame 25 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNT1 | cyclin T1 |
| CD83 | CD83 molecule |
| CLEC4A | C-type lectin domain family 4, member A |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CREM | cAMP responsive element modulator |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| EFNB2 | ephrin-B2 |
| EGR1 | early growth response 1 |
| EPHA4 | EPH receptor A4 |
| FLCN | folliculin |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H4C | histone cluster 1, H4c |
| IL1B | interleukin 1, beta |
| IL6ST | interleukin 6 signal transducer |
| KAT6A | K(lysine) acetyltransferase 6A |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLHL24 | kelch-like family member 24 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LDLR | low density lipoprotein receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MED1 | mediator complex subunit 1 |
| MKI67 | marker of proliferation Ki-67 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NFYA | nuclear transcription factor Y, alpha |
| NGLY1 | N-glycanase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUPL1 | nucleoporin like 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PER1 | period circadian clock 1 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PNISR | PNN-interacting serine/arginine-rich protein |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RBM5 | RNA binding motif protein 5 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RND1 | Rho family GTPase 1 |
| RPA4 | replication protein A4, 30kDa |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCG5 | secretogranin V |
| SEC24A | SEC24 family member A |
| SFPQ | splicing factor proline/glutamine-rich |
| SIK3 | SIK family kinase 3 |
| SKIL | SKI-like proto-oncogene |
| SMC4 | structural maintenance of chromosomes 4 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TM2D1 | TM2 domain containing 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TOB2 | transducer of ERBB2, 2 |
| TRIM38 | tripartite motif containing 38 |
| TUFT1 | tuftelin 1 |
| TWF1 | twinfilin actin binding protein 1 |
| TXNIP | thioredoxin interacting protein |
| UBAP1 | ubiquitin associated protein 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WASL | Wiskott-Aldrich syndrome-like |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZNF143 | zinc finger protein 143 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CALHM2 | calcium homeostasis modulator 2 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA1 | cyclin A1 |
| CCNE2 | cyclin E2 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CECR5 | cat eye syndrome chromosome region, candidate 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COG2 | component of oligomeric golgi complex 2 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| EMC2 | ER membrane protein complex subunit 2 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GFI1 | growth factor independent 1 transcription repressor |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| ICT1 | immature colon carcinoma transcript 1 |
| JRKL | JRK-like |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KLF11 | Kruppel-like factor 11 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| MAT2A | methionine adenosyltransferase II, alpha |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MINA | MYC induced nuclear antigen |
| MKKS | McKusick-Kaufman syndrome |
| MNS1 | meiosis-specific nuclear structural 1 |
| MRPL15 | mitochondrial ribosomal protein L15 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MRPS31 | mitochondrial ribosomal protein S31 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MSRB1 | methionine sulfoxide reductase B1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAGK | N-acetylglucosamine kinase |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NELFE | negative elongation factor complex member E |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NFE2 | nuclear factor, erythroid 2 |
| NMI | N-myc (and STAT) interactor |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OIP5 | Opa interacting protein 5 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAAF1 | proteasomal ATPase-associated factor 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PDCD5 | programmed cell death 5 |
| PEX11B | peroxisomal biogenesis factor 11 beta |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POGK | pogo transposable element with KRAB domain |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRDM13 | PR domain containing 13 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKX | protein kinase, X-linked |
| PRR3 | proline rich 3 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RGS13 | regulator of G-protein signaling 13 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SETMAR | SET domain and mariner transposase fusion gene |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| SRSF8 | serine/arginine-rich splicing factor 8 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| TEFM | transcription elongation factor, mitochondrial |
| TFB1M | transcription factor B1, mitochondrial |
| TMEM186 | transmembrane protein 186 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM5 | tripartite motif containing 5 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| UBL4A | ubiquitin-like 4A |
| UFSP2 | UFM1-specific peptidase 2 |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| WDR3 | WD repeat domain 3 |
| XPA | xeroderma pigmentosum, complementation group A |
| ZNF23 | zinc finger protein 23 |
| ZNF248 | zinc finger protein 248 |
| ZNF302 | zinc finger protein 302 |
| ZNF33B | zinc finger protein 33B |
| ZNF7 | zinc finger protein 7 |
| ZNF85 | zinc finger protein 85 |
| ZW10 | zw10 kinetochore protein |
| ZXDC | ZXD family zinc finger C |
