| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the digitoxigenin-3275 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADM | adrenomedullin |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMD1 | adenosylmethionine decarboxylase 1 |
| AMOTL2 | angiomotin like 2 |
| ATF3 | activating transcription factor 3 |
| AVPI1 | arginine vasopressin-induced 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCDC186 | coiled-coil domain containing 186 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| COL1A1 | collagen, type I, alpha 1 |
| CTGF | connective tissue growth factor |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTTN | cortactin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EFNB2 | ephrin-B2 |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| FAM46A | family with sequence similarity 46, member A |
| FASTKD2 | FAST kinase domains 2 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GRB7 | growth factor receptor-bound protein 7 |
| HCFC2 | host cell factor C2 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H4C | histone cluster 1, H4c |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| INSIG1 | insulin induced gene 1 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| LDLR | low density lipoprotein receptor |
| LINS | lines homolog (Drosophila) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCL1 | myeloid cell leukemia 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDH9 | protocadherin 9 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RGS16 | regulator of G-protein signaling 16 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RND3 | Rho family GTPase 3 |
| S100A9 | S100 calcium binding protein A9 |
| SERTAD3 | SERTA domain containing 3 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| STK3 | serine/threonine kinase 3 |
| TCF12 | transcription factor 12 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TGFB2 | transforming growth factor, beta 2 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TXNIP | thioredoxin interacting protein |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZFP36 | ZFP36 ring finger protein |
| ZFX | zinc finger protein, X-linked |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF654 | zinc finger protein 654 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BBX | bobby sox homolog (Drosophila) |
| C11ORF95 | chromosome 11 open reading frame 95 |
| CBR3 | carbonyl reductase 3 |
| CCNO | cyclin O |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CSK | c-src tyrosine kinase |
| DSE | dermatan sulfate epimerase |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR3 | early growth response 3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FANCF | Fanconi anemia, complementation group F |
| FKBPL | FK506 binding protein like |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPR19 | G protein-coupled receptor 19 |
| HOXC6 | homeobox C6 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IL4R | interleukin 4 receptor |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF9 | interferon regulatory factor 9 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIZ | kizuna centrosomal protein |
| KRCC1 | lysine-rich coiled-coil 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC730101 | uncharacterized LOC730101 |
| MEIS1 | Meis homeobox 1 |
| MKKS | McKusick-Kaufman syndrome |
| MLYCD | malonyl-CoA decarboxylase |
| MNS1 | meiosis-specific nuclear structural 1 |
| MRPS31 | mitochondrial ribosomal protein S31 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NELFE | negative elongation factor complex member E |
| NOL8 | nucleolar protein 8 |
| ORC3 | origin recognition complex, subunit 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PEX1 | peroxisomal biogenesis factor 1 |
| PEX12 | peroxisomal biogenesis factor 12 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRKX | protein kinase, X-linked |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC46A3 | solute carrier family 46, member 3 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| TBC1D31 | TBC1 domain family, member 31 |
| TBCCD1 | TBCC domain containing 1 |
| TDRD7 | tudor domain containing 7 |
| TFB1M | transcription factor B1, mitochondrial |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TRIM27 | tripartite motif containing 27 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBL4A | ubiquitin-like 4A |
| USP18 | ubiquitin specific peptidase 18 |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| XPA | xeroderma pigmentosum, complementation group A |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF165 | zinc finger protein 165 |
| ZNF184 | zinc finger protein 184 |
| ZNF189 | zinc finger protein 189 |
| ZNF23 | zinc finger protein 23 |
| ZNF239 | zinc finger protein 239 |
| ZNF248 | zinc finger protein 248 |
| ZNF302 | zinc finger protein 302 |
| ZNF573 | zinc finger protein 573 |
| ZNF623 | zinc finger protein 623 |
| ZNF839 | zinc finger protein 839 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
