| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the digitoxigenin-4217 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ACRV1 | acrosomal vesicle protein 1 |
| ADM | adrenomedullin |
| AGXT | alanine-glyoxylate aminotransferase |
| ALPI | alkaline phosphatase, intestinal |
| ALX4 | ALX homeobox 4 |
| AQP4 | aquaporin 4 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| BGN | biglycan |
| BTG2 | BTG family, member 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CCNL1 | cyclin L1 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP152 | centrosomal protein 152kDa |
| CLK1 | CDC-like kinase 1 |
| CTGF | connective tissue growth factor |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCC | DCC netrin 1 receptor |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLX2 | distal-less homeobox 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DSC1 | desmocollin 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EDDM3B | epididymal protein 3B |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| EPHB1 | EPH receptor B1 |
| EPO | erythropoietin |
| FAM46C | family with sequence similarity 46, member C |
| FLCN | folliculin |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GPR87 | G protein-coupled receptor 87 |
| H1FX | H1 histone family, member X |
| HBEGF | heparin-binding EGF-like growth factor |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST2H2BE | histone cluster 2, H2be |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLHL20 | kelch-like family member 20 |
| KLHL23 | kelch-like family member 23 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MED27 | mediator complex subunit 27 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPC1 | Niemann-Pick disease, type C1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCDHA5 | protocadherin alpha 5 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PLK4 | polo-like kinase 4 |
| PLVAP | plasmalemma vesicle associated protein |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBMY2FP | RNA binding motif protein, Y-linked, family 2, member F pseudogene |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RGR | retinal G protein coupled receptor |
| RGS16 | regulator of G-protein signaling 16 |
| RHOB | ras homolog family member B |
| RUNX1 | runt-related transcription factor 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STK17B | serine/threonine kinase 17b |
| SYT13 | synaptotagmin XIII |
| TAS2R3 | taste receptor, type 2, member 3 |
| TEX14 | testis expressed 14 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSPY1 | testis specific protein, Y-linked 1 |
| TXNIP | thioredoxin interacting protein |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| ZFP36 | ZFP36 ring finger protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANXA10 | annexin A10 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBR3 | carbonyl reductase 3 |
| CCDC176 | coiled-coil domain containing 176 |
| CCNA1 | cyclin A1 |
| CDC7 | cell division cycle 7 |
| CEP112 | centrosomal protein 112kDa |
| CEP70 | centrosomal protein 70kDa |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| ERCC5 | excision repair cross-complementation group 5 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM50B | family with sequence similarity 50, member B |
| FAM69A | family with sequence similarity 69, member A |
| FANCF | Fanconi anemia, complementation group F |
| FANCL | Fanconi anemia, complementation group L |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GID4 | GID complex subunit 4 |
| GOLGA5 | golgin A5 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA1 | homeobox A1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IFT54 | intraflagellar transport 54 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IL17RA | interleukin 17 receptor A |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMNB1 | lamin B1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MXD3 | MAX dimerization protein 3 |
| NDP | Norrie disease (pseudoglioma) |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OSMR | oncostatin M receptor |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCD1 | phospholipase C, delta 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| POGK | pogo transposable element with KRAB domain |
| POLH | polymerase (DNA directed), eta |
| PRKX | protein kinase, X-linked |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| S100PBP | S100P binding protein |
| SCRN3 | secernin 3 |
| SEPHS2 | selenophosphate synthetase 2 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SHROOM2 | shroom family member 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNPH | syntaphilin |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TFB1M | transcription factor B1, mitochondrial |
| THAP10 | THAP domain containing 10 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM186 | transmembrane protein 186 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRIM45 | tripartite motif containing 45 |
| TRIM66 | tripartite motif containing 66 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR3 | WD repeat domain 3 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZNF232 | zinc finger protein 232 |
| ZNF239 | zinc finger protein 239 |
| ZNF365 | zinc finger protein 365 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZXDC | ZXD family zinc finger C |
