| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the digitoxigenin-4801 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ACVR2A | activin A receptor, type IIA |
| ADM | adrenomedullin |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMD1 | adenosylmethionine decarboxylase 1 |
| AMOTL2 | angiomotin like 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| ATF3 | activating transcription factor 3 |
| ATF7IP | activating transcription factor 7 interacting protein |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCNL1 | cyclin L1 |
| CCNT2 | cyclin T2 |
| CDKN2AIP | CDKN2A interacting protein |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CTGF | connective tissue growth factor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN1 | endothelin 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPHA2 | EPH receptor A2 |
| ETNK1 | ethanolamine kinase 1 |
| EWSR1 | EWS RNA-binding protein 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HCFC2 | host cell factor C2 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H1T | histone cluster 1, H1t |
| HOXC13 | homeobox C13 |
| HSF2 | heat shock transcription factor 2 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| KLHL24 | kelch-like family member 24 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCL1 | myeloid cell leukemia 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| RARG | retinoic acid receptor, gamma |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM48 | RNA binding motif protein 48 |
| RBM5 | RNA binding motif protein 5 |
| RGS16 | regulator of G-protein signaling 16 |
| RLF | rearranged L-myc fusion |
| SERTAD3 | SERTA domain containing 3 |
| SFPQ | splicing factor proline/glutamine-rich |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC35F5 | solute carrier family 35, member F5 |
| STRN3 | striatin, calmodulin binding protein 3 |
| STX3 | syntaxin 3 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TGFB2 | transforming growth factor, beta 2 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TXNIP | thioredoxin interacting protein |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| YTHDC1 | YTH domain containing 1 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZFX | zinc finger protein, X-linked |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF143 | zinc finger protein 143 |
| ZNF281 | zinc finger protein 281 |
| ZNF335 | zinc finger protein 335 |
| ZNF654 | zinc finger protein 654 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CBR3 | carbonyl reductase 3 |
| CBY1 | chibby homolog 1 (Drosophila) |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR3 | early growth response 3 |
| EHD3 | EH-domain containing 3 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| EXOC2 | exocyst complex component 2 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FANCF | Fanconi anemia, complementation group F |
| FJX1 | four jointed box 1 (Drosophila) |
| FPGT | fucose-1-phosphate guanylyltransferase |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| IPP | intracisternal A particle-promoted polypeptide |
| JRKL | JRK-like |
| KRCC1 | lysine-rich coiled-coil 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| MAP6D1 | MAP6 domain containing 1 |
| MKKS | McKusick-Kaufman syndrome |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MUTYH | mutY homolog |
| NDE1 | nudE neurodevelopment protein 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NELFE | negative elongation factor complex member E |
| NINL | ninein-like |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAAF1 | proteasomal ATPase-associated factor 1 |
| PALB2 | partner and localizer of BRCA2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PLA2G3 | phospholipase A2, group III |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| S100PBP | S100P binding protein |
| SACS | sacsin molecular chaperone |
| SALL2 | spalt-like transcription factor 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SNUPN | snurportin 1 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TBC1D31 | TBC1 domain family, member 31 |
| TFB1M | transcription factor B1, mitochondrial |
| THAP7 | THAP domain containing 7 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THYN1 | thymocyte nuclear protein 1 |
| TRIM16 | tripartite motif containing 16 |
| TRIM27 | tripartite motif containing 27 |
| TRIM45 | tripartite motif containing 45 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TRMT61B | tRNA methyltransferase 61B |
| TTC4 | tetratricopeptide repeat domain 4 |
| USP20 | ubiquitin specific peptidase 20 |
| WDR3 | WD repeat domain 3 |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZIC1 | Zic family member 1 |
| ZNF23 | zinc finger protein 23 |
| ZNF239 | zinc finger protein 239 |
| ZNF248 | zinc finger protein 248 |
| ZNF302 | zinc finger protein 302 |
| ZNF623 | zinc finger protein 623 |
| ZNF839 | zinc finger protein 839 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
| ZXDC | ZXD family zinc finger C |
