digitoxigenin Gene Set
Genes
27 genes differentially expressed following the digitoxigenin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GADD45B
|
growth arrest and DNA-damage-inducible, beta
|
4.99414
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
4.70861
|
|
NUP58
|
nucleoporin 58
|
4.05305
|
|
GMEB1
|
glucocorticoid modulatory element binding protein 1
|
3.69002
|
|
CCNA2
|
cyclin A2
|
3.59778
|
|
ZMYM5
|
zinc finger, MYM-type 5
|
3.58867
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
3.57827
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
3.56135
|
|
ATF3
|
activating transcription factor 3
|
3.50746
|
|
LRIG2
|
leucine-rich repeats and immunoglobulin-like domains 2
|
3.3743
|
|
GABPB1
|
GA binding protein transcription factor, beta subunit 1
|
3.26128
|
|
AFF4
|
AF4/FMR2 family, member 4
|
3.25335
|
|
MCM2
|
minichromosome maintenance complex component 2
|
3.25283
|
|
EGR1
|
early growth response 1
|
3.23949
|
|
ABL2
|
ABL proto-oncogene 2, non-receptor tyrosine kinase
|
3.19469
|
|
ANKHD1
|
ankyrin repeat and KH domain containing 1
|
3.0475
|
|
PTBP2
|
polypyrimidine tract binding protein 2
|
3.0437
|
|
WDR33
|
WD repeat domain 33
|
3.01225
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSPA8
|
heat shock 70kDa protein 8
|
-4.09211
|
|
CBR3
|
carbonyl reductase 3
|
-3.76046
|
|
MSRB1
|
methionine sulfoxide reductase B1
|
-3.67911
|
|
TRMT1L
|
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
|
-3.51349
|
|
TMEM187
|
transmembrane protein 187
|
-3.36719
|
|
LDAH
|
lipid droplet associated hydrolase
|
-3.18317
|
|
TRAK2
|
trafficking protein, kinesin binding 2
|
-3.17938
|
|
CBR1
|
carbonyl reductase 1
|
-3.04219
|
|
TRAPPC12
|
trafficking protein particle complex 12
|
-3.0053
|
