| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the digoxigenin-3397 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADM | adrenomedullin |
| AMOTL2 | angiomotin like 2 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ATF3 | activating transcription factor 3 |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CALCR | calcitonin receptor |
| CCNT2 | cyclin T2 |
| CD47 | CD47 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COPA | coatomer protein complex, subunit alpha |
| CTSZ | cathepsin Z |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| FAM46A | family with sequence similarity 46, member A |
| FASTKD2 | FAST kinase domains 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL2 | FOS-like antigen 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAP43 | growth associated protein 43 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBP1 | HMG-box transcription factor 1 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4E | histone cluster 1, H4e |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC13 | homeobox C13 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL2RB | interleukin 2 receptor, beta |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| LDLR | low density lipoprotein receptor |
| LINS | lines homolog (Drosophila) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAOB | monoamine oxidase B |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OVOL1 | ovo-like zinc finger 1 |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDH9 | protocadherin 9 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPS2 | ribosomal protein S2 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| SERTAD3 | SERTA domain containing 3 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SKIL | SKI-like proto-oncogene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SP1 | Sp1 transcription factor |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STK3 | serine/threonine kinase 3 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAOK2 | TAO kinase 2 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| THBS1 | thrombospondin 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TPP1 | tripeptidyl peptidase I |
| TRBC1 | T cell receptor beta constant 1 |
| TXNIP | thioredoxin interacting protein |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| WSB1 | WD repeat and SOCS box containing 1 |
| YTHDC1 | YTH domain containing 1 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BLNK | B-cell linker |
| BMP4 | bone morphogenetic protein 4 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1QB | complement component 1, q subcomponent, B chain |
| C3 | complement component 3 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CDK6 | cyclin-dependent kinase 6 |
| CES3 | carboxylesterase 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP13 | dual specificity phosphatase 13 |
| DVL1 | dishevelled segment polarity protein 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FADS2 | fatty acid desaturase 2 |
| FBXO22 | F-box protein 22 |
| FOXI1 | forkhead box I1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GFI1 | growth factor independent 1 transcription repressor |
| GID4 | GID complex subunit 4 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLB1L | galactosidase, beta 1-like |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL22 | interleukin 22 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIF13A | kinesin family member 13A |
| KRT24 | keratin 24, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRRC15 | leucine rich repeat containing 15 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MEFV | Mediterranean fever |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MSI1 | musashi RNA-binding protein 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MVP | major vault protein |
| N4BP3 | NEDD4 binding protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NYNRIN | NYN domain and retroviral integrase containing |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALM | paralemmin |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| POLM | polymerase (DNA directed), mu |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RANBP17 | RAN binding protein 17 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RND1 | Rho family GTPase 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SECTM1 | secreted and transmembrane 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPEG | SPEG complex locus |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBX19 | T-box 19 |
| THBS3 | thrombospondin 3 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM8B | transmembrane protein 8B |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TRIM45 | tripartite motif containing 45 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK3B | uroplakin 3B |
| VASH1 | vasohibin 1 |
| WDR91 | WD repeat domain 91 |
| XYLT2 | xylosyltransferase II |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF304 | zinc finger protein 304 |
| ZNF41 | zinc finger protein 41 |
| ZNF446 | zinc finger protein 446 |
| ZNF510 | zinc finger protein 510 |
| ZNF696 | zinc finger protein 696 |
