| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the digoxigenin-4680 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADM | adrenomedullin |
| AFF4 | AF4/FMR2 family, member 4 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AMOTL2 | angiomotin like 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARC | activity-regulated cytoskeleton-associated protein |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| CCNL1 | cyclin L1 |
| CDKN2AIP | CDKN2A interacting protein |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTH | cystathionine gamma-lyase |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GPR87 | G protein-coupled receptor 87 |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| IL6R | interleukin 6 receptor |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KITLG | KIT ligand |
| KLF4 | Kruppel-like factor 4 (gut) |
| LPIN1 | lipin 1 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCL1 | myeloid cell leukemia 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OVOL1 | ovo-like zinc finger 1 |
| PER1 | period circadian clock 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PVR | poliovirus receptor |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHOB | ras homolog family member B |
| RUNX1 | runt-related transcription factor 1 |
| SAFB2 | scaffold attachment factor B2 |
| SFPQ | splicing factor proline/glutamine-rich |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STC2 | stanniocalcin 2 |
| STK17B | serine/threonine kinase 17b |
| STX3 | syntaxin 3 |
| TEX14 | testis expressed 14 |
| TGFA | transforming growth factor, alpha |
| TGFB2 | transforming growth factor, beta 2 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM156 | transmembrane protein 156 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TSC22D2 | TSC22 domain family, member 2 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| WSB1 | WD repeat and SOCS box containing 1 |
| YTHDC1 | YTH domain containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF24 | zinc finger protein 24 |
| ZNF442 | zinc finger protein 442 |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| AMT | aminomethyltransferase |
| APOL6 | apolipoprotein L, 6 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BEND5 | BEN domain containing 5 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CBR3 | carbonyl reductase 3 |
| CCNO | cyclin O |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEL | carboxyl ester lipase |
| CISH | cytokine inducible SH2-containing protein |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDN | dendrin |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFNA3 | ephrin-A3 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM131B | family with sequence similarity 131, member B |
| FAM53B | family with sequence similarity 53, member B |
| FANCF | Fanconi anemia, complementation group F |
| FMO4 | flavin containing monooxygenase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HOXA1 | homeobox A1 |
| HOXA11 | homeobox A11 |
| HOXA2 | homeobox A2 |
| HOXC4 | homeobox C4 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL17RB | interleukin 17 receptor B |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| JRKL | JRK-like |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0754 | KIAA0754 |
| KIZ | kizuna centrosomal protein |
| KLF13 | Kruppel-like factor 13 |
| KRCC1 | lysine-rich coiled-coil 1 |
| KRT20 | keratin 20, type I |
| LHX6 | LIM homeobox 6 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC100127972 | uncharacterized LOC100127972 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LTC4S | leukotriene C4 synthase |
| MAP6D1 | MAP6 domain containing 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MGP | matrix Gla protein |
| MUC3A | mucin 3A, cell surface associated |
| MYOZ3 | myozenin 3 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| RAB3A | RAB3A, member RAS oncogene family |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGS20 | regulator of G-protein signaling 20 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEPHS2 | selenophosphate synthetase 2 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SHROOM2 | shroom family member 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA1 | spermatogenesis associated 1 |
| STAB2 | stabilin 2 |
| SYT17 | synaptotagmin XVII |
| THAP7 | THAP domain containing 7 |
| TRIM21 | tripartite motif containing 21 |
| TRIM45 | tripartite motif containing 45 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF239 | zinc finger protein 239 |
| ZNF365 | zinc finger protein 365 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
