digoxigenin-5275 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the digoxigenin-5275 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADM adrenomedullin
AFF4 AF4/FMR2 family, member 4
AKAP8L A kinase (PRKA) anchor protein 8-like
AMOTL2 angiomotin like 2
ARTN artemin
ATF3 activating transcription factor 3
ATF7IP activating transcription factor 7 interacting protein
AVPI1 arginine vasopressin-induced 1
BCL6 B-cell CLL/lymphoma 6
CCDC88C coiled-coil domain containing 88C
CCNT2 cyclin T2
CDK19 cyclin-dependent kinase 19
CDKN2AIP CDKN2A interacting protein
CGA glycoprotein hormones, alpha polypeptide
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DUSP8 dual specificity phosphatase 8
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDN1 endothelin 1
EED embryonic ectoderm development
EFNA1 ephrin-A1
EGR1 early growth response 1
EGR2 early growth response 2
EPHA2 EPH receptor A2
EWSR1 EWS RNA-binding protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
HBP1 HMG-box transcription factor 1
HIC2 hypermethylated in cancer 2
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HOXC13 homeobox C13
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
IER2 immediate early response 2
IP6K2 inositol hexakisphosphate kinase 2
JUN jun proto-oncogene
JUND jun D proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
KDM6A lysine (K)-specific demethylase 6A
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLHL24 kelch-like family member 24
KMT2A lysine (K)-specific methyltransferase 2A
KPNA5 karyopherin alpha 5 (importin alpha 6)
LINS lines homolog (Drosophila)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MCL1 myeloid cell leukemia 1
MORC3 MORC family CW-type zinc finger 3
MXD1 MAX dimerization protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OVOL1 ovo-like zinc finger 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RARA retinoic acid receptor, alpha
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM5 RNA binding motif protein 5
RLF rearranged L-myc fusion
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SERTAD3 SERTA domain containing 3
SFPQ splicing factor proline/glutamine-rich
SKIL SKI-like proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SPRY4 sprouty homolog 4 (Drosophila)
STX3 syntaxin 3
SWAP70 SWAP switching B-cell complex 70kDa subunit
TRA2A transformer 2 alpha homolog (Drosophila)
TSC22D2 TSC22 domain family, member 2
TXNIP thioredoxin interacting protein
UBE2H ubiquitin-conjugating enzyme E2H
WAC WW domain containing adaptor with coiled-coil
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
YTHDC1 YTH domain containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZEB1 zinc finger E-box binding homeobox 1
ZMYM2 zinc finger, MYM-type 2
ZMYM5 zinc finger, MYM-type 5
ZNF335 zinc finger protein 335
ZNF654 zinc finger protein 654

decreased expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD46 ankyrin repeat domain 46
ARMCX1 armadillo repeat containing, X-linked 1
ASB13 ankyrin repeat and SOCS box containing 13
CAMTA1 calmodulin binding transcription activator 1
CANT1 calcium activated nucleotidase 1
CAPRIN2 caprin family member 2
CBR3 carbonyl reductase 3
CBR4 carbonyl reductase 4
CPT2 carnitine palmitoyltransferase 2
DEAF1 DEAF1 transcription factor
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAAF2 dynein, axonemal, assembly factor 2
ECHDC3 enoyl CoA hydratase domain containing 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ETAA1 Ewing tumor-associated antigen 1
FADD Fas (TNFRSF6)-associated via death domain
FAM114A2 family with sequence similarity 114, member A2
FAM86B1 family with sequence similarity 86, member B1
FANCF Fanconi anemia, complementation group F
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
GOLGA5 golgin A5
GPR19 G protein-coupled receptor 19
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
HOXC6 homeobox C6
IRX4 iroquois homeobox 4
JRKL JRK-like
KRCC1 lysine-rich coiled-coil 1
LINC00339 long intergenic non-protein coding RNA 339
LOC100287590 uncharacterized LOC100287590
MEIS1 Meis homeobox 1
MKKS McKusick-Kaufman syndrome
MLYCD malonyl-CoA decarboxylase
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
ORC3 origin recognition complex, subunit 3
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PAAF1 proteasomal ATPase-associated factor 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALB2 partner and localizer of BRCA2
PER3 period circadian clock 3
PMCH pro-melanin-concentrating hormone
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRMT7 protein arginine methyltransferase 7
PRR3 proline rich 3
PTCD2 pentatricopeptide repeat domain 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAP1GAP2 RAP1 GTPase activating protein 2
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPP40 ribonuclease P/MRP 40kDa subunit
RPUSD2 RNA pseudouridylate synthase domain containing 2
RSAD1 radical S-adenosyl methionine domain containing 1
RUFY2 RUN and FYVE domain containing 2
S100PBP S100P binding protein
SACS sacsin molecular chaperone
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SOWAHC sosondowah ankyrin repeat domain family member C
SPATA7 spermatogenesis associated 7
STARD13 StAR-related lipid transfer (START) domain containing 13
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
TFB1M transcription factor B1, mitochondrial
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAPPC11 trafficking protein particle complex 11
TRIM16 tripartite motif containing 16
TRIM27 tripartite motif containing 27
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TXNRD3 thioredoxin reductase 3
WDR3 WD repeat domain 3
XBP1 X-box binding protein 1
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZIC1 Zic family member 1
ZNF23 zinc finger protein 23
ZNF239 zinc finger protein 239
ZNF248 zinc finger protein 248
ZNF573 zinc finger protein 573
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZXDC ZXD family zinc finger C